Concept of emergence of a new coronavirus infection
This report presents a brief review of literature and the authors’ concept of the emergence of the novel coronavirus 19 infection. The purpose of the work is to show the significance of lysozyme deficiency in the pathogenesis of COVID-19 based on data from literature sources and the results of the a...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Union of pediatricians of Russia
2021-01-01
|
| Series: | Педиатрическая фармакология |
| Subjects: | |
| Online Access: | https://www.pedpharma.ru/jour/article/view/1926 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849243793603166208 |
|---|---|
| author | Valentina G. Dorofeychouck Stella A. Sher |
| author_facet | Valentina G. Dorofeychouck Stella A. Sher |
| author_sort | Valentina G. Dorofeychouck |
| collection | DOAJ |
| description | This report presents a brief review of literature and the authors’ concept of the emergence of the novel coronavirus 19 infection. The purpose of the work is to show the significance of lysozyme deficiency in the pathogenesis of COVID-19 based on data from literature sources and the results of the authors’ past studies. The relevance of the study is due to the planetary scale of the spread of coronavirus infection, the appearance of SARS-CoV-2 with new aggressive signs, the difficulties of their treatment and prevention. Anatomo-functional connection of protective mechanisms of lysozyme, mucopolysaccharides of histohaematic barriers with preservation of immune, biochemical and tissue homeostasis is established. The loss of lysozyme, which has genetically determined enzymatic specificity, contributes to the development of damaging processes of immune, biochemical and tissue nature with manifestation in all organs and systems of the body. Inclusion of exogenous lysozyme in basic therapy and prophylaxis COVID-19 is proposed. |
| format | Article |
| id | doaj-art-fa946ec2d89c4aa8a18bce85d0ad8019 |
| institution | Kabale University |
| issn | 1727-5776 2500-3089 |
| language | Russian |
| publishDate | 2021-01-01 |
| publisher | Union of pediatricians of Russia |
| record_format | Article |
| series | Педиатрическая фармакология |
| spelling | doaj-art-fa946ec2d89c4aa8a18bce85d0ad80192025-08-20T03:59:21ZrusUnion of pediatricians of RussiaПедиатрическая фармакология1727-57762500-30892021-01-0117654755110.15690/pf.v17i6.22031752Concept of emergence of a new coronavirus infectionValentina G. Dorofeychouck0Stella A. Sher1Research Institute of Pediatrics and Children’s Health in «Central Clinical Hospital of the Russian Academy of Sciences»Research Institute of Pediatrics and Children’s Health in «Central Clinical Hospital of the Russian Academy of Sciences»This report presents a brief review of literature and the authors’ concept of the emergence of the novel coronavirus 19 infection. The purpose of the work is to show the significance of lysozyme deficiency in the pathogenesis of COVID-19 based on data from literature sources and the results of the authors’ past studies. The relevance of the study is due to the planetary scale of the spread of coronavirus infection, the appearance of SARS-CoV-2 with new aggressive signs, the difficulties of their treatment and prevention. Anatomo-functional connection of protective mechanisms of lysozyme, mucopolysaccharides of histohaematic barriers with preservation of immune, biochemical and tissue homeostasis is established. The loss of lysozyme, which has genetically determined enzymatic specificity, contributes to the development of damaging processes of immune, biochemical and tissue nature with manifestation in all organs and systems of the body. Inclusion of exogenous lysozyme in basic therapy and prophylaxis COVID-19 is proposed.https://www.pedpharma.ru/jour/article/view/1926new coronavirus infectioncovid-19sars-cov-2lysozymepreventiontreatmentq12 |
| spellingShingle | Valentina G. Dorofeychouck Stella A. Sher Concept of emergence of a new coronavirus infection Педиатрическая фармакология new coronavirus infection covid-19 sars-cov-2 lysozyme prevention treatmentq12 |
| title | Concept of emergence of a new coronavirus infection |
| title_full | Concept of emergence of a new coronavirus infection |
| title_fullStr | Concept of emergence of a new coronavirus infection |
| title_full_unstemmed | Concept of emergence of a new coronavirus infection |
| title_short | Concept of emergence of a new coronavirus infection |
| title_sort | concept of emergence of a new coronavirus infection |
| topic | new coronavirus infection covid-19 sars-cov-2 lysozyme prevention treatmentq12 |
| url | https://www.pedpharma.ru/jour/article/view/1926 |
| work_keys_str_mv | AT valentinagdorofeychouck conceptofemergenceofanewcoronavirusinfection AT stellaasher conceptofemergenceofanewcoronavirusinfection |