Primary Mediastinal Synovial Sarcoma; a rare case

Background: Synovial sarcoma, a rare subtype of soft-tissue sarcomas, typically manifests in the extremities of young individuals. Mediastinal occurrences are exceedingly uncommon, with sparse cases documented.Case: This article details the atypical presentation of a mediastinal synovial sarcoma in...

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Main Authors: Ali Goudarzi, Leila Ostovar
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2024-06-01
Series:Journal of Cardio-Thoracic Medicine
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Online Access:https://jctm.mums.ac.ir/article_24905_811607b4cde8df38a7ceb6815d9cd15c.pdf
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author Ali Goudarzi
Leila Ostovar
author_facet Ali Goudarzi
Leila Ostovar
author_sort Ali Goudarzi
collection DOAJ
description Background: Synovial sarcoma, a rare subtype of soft-tissue sarcomas, typically manifests in the extremities of young individuals. Mediastinal occurrences are exceedingly uncommon, with sparse cases documented.Case: This article details the atypical presentation of a mediastinal synovial sarcoma in a 68-year-old female patient, diverging from the common demographic and anatomical predilections. Initial symptoms of a dry cough and fatigue led to the discovery of a mediastinal mass via chest CT scan. Subsequent pathological examination confirmed the diagnosis of mediastinal synovial sarcoma. Despite the identification of this rare tumor, the patient's condition progressed rapidly, resulting in her demise within two months post-diagnosis.Conclusion: This case underlines the critical need for increased awareness and research into the mediastinal variant to improve diagnostic accuracy and treatment efficacy. Despite synovial sarcoma being predominantly identified in the extremities, occurrences in the mediastinum present unique diagnostic dilemmas and therapeutic hurdles due to limited literature and atypical clinical presentations. The utilization of advanced imaging modalities, immunostaining techniques, and multimodal treatment approaches is essential in the management of mediastinal synovial sarcoma.
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spelling doaj-art-fa6ed03e493c4f34a43861eb6c61c55c2024-12-31T10:05:54ZengMashhad University of Medical SciencesJournal of Cardio-Thoracic Medicine2345-24472322-57502024-06-011221356136010.22038/jctm.2024.82309.146824905Primary Mediastinal Synovial Sarcoma; a rare caseAli Goudarzi0Leila Ostovar1Department of Radiology, Shiraz University of Medical Sciences, Shiraz, IranDepartment of Radiology, Rafsanjan University of Medical Sciences, Rafsanjan, IranBackground: Synovial sarcoma, a rare subtype of soft-tissue sarcomas, typically manifests in the extremities of young individuals. Mediastinal occurrences are exceedingly uncommon, with sparse cases documented.Case: This article details the atypical presentation of a mediastinal synovial sarcoma in a 68-year-old female patient, diverging from the common demographic and anatomical predilections. Initial symptoms of a dry cough and fatigue led to the discovery of a mediastinal mass via chest CT scan. Subsequent pathological examination confirmed the diagnosis of mediastinal synovial sarcoma. Despite the identification of this rare tumor, the patient's condition progressed rapidly, resulting in her demise within two months post-diagnosis.Conclusion: This case underlines the critical need for increased awareness and research into the mediastinal variant to improve diagnostic accuracy and treatment efficacy. Despite synovial sarcoma being predominantly identified in the extremities, occurrences in the mediastinum present unique diagnostic dilemmas and therapeutic hurdles due to limited literature and atypical clinical presentations. The utilization of advanced imaging modalities, immunostaining techniques, and multimodal treatment approaches is essential in the management of mediastinal synovial sarcoma.https://jctm.mums.ac.ir/article_24905_811607b4cde8df38a7ceb6815d9cd15c.pdfmediastinal massoncologysynovial sarcoma
spellingShingle Ali Goudarzi
Leila Ostovar
Primary Mediastinal Synovial Sarcoma; a rare case
Journal of Cardio-Thoracic Medicine
mediastinal mass
oncology
synovial sarcoma
title Primary Mediastinal Synovial Sarcoma; a rare case
title_full Primary Mediastinal Synovial Sarcoma; a rare case
title_fullStr Primary Mediastinal Synovial Sarcoma; a rare case
title_full_unstemmed Primary Mediastinal Synovial Sarcoma; a rare case
title_short Primary Mediastinal Synovial Sarcoma; a rare case
title_sort primary mediastinal synovial sarcoma a rare case
topic mediastinal mass
oncology
synovial sarcoma
url https://jctm.mums.ac.ir/article_24905_811607b4cde8df38a7ceb6815d9cd15c.pdf
work_keys_str_mv AT aligoudarzi primarymediastinalsynovialsarcomaararecase
AT leilaostovar primarymediastinalsynovialsarcomaararecase