Opposite Responses of Interferon and Proinflammatory Cytokines Induced by Human Metapneumovirus and Respiratory Syncytial Virus in Macrophages

Opposite Responses of Interferon and Proinflammatory Cytokines Induced by Human Metapneumovirus and Respiratory Syncytial Virus in Macrophages

Macrophages are a principal pulmonary source of type I and III interferons (IFNs), initiating and coordinating the early antiviral response to respiratory viral infections. Yet the contribution of macrophage-derived IFNs to host defense during human metapneumovirus (HMPV) infection remains poorly de...

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Bibliographic Details
Main Authors: Iván Martínez-Espinoza, Antonieta Guerrero-Plata
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Pathogens
Subjects:
HMPV
RSV
macrophages
MDMs
proinflammatory
innate immunity
Online Access:https://www.mdpi.com/2076-0817/14/7/694
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