Mollicutes/HIV Coinfection and the Development of AIDS: Still Far from a Definitive Response
Background. Mycoplasmas are known to cause various infections in humans, mainly in the respiratory and urogenital tracts. The different species are usually host-specific and cause diseases in well-defined sites. New species have been isolated, including those from HIV-infected persons. Summary. Its...
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Format: | Article |
Language: | English |
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Wiley
2016-01-01
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Series: | Canadian Journal of Infectious Diseases and Medical Microbiology |
Online Access: | http://dx.doi.org/10.1155/2016/8192323 |
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author | Caio Mauricio Mendes de Cordova Caroline Galgowski Leonardo Lange |
author_facet | Caio Mauricio Mendes de Cordova Caroline Galgowski Leonardo Lange |
author_sort | Caio Mauricio Mendes de Cordova |
collection | DOAJ |
description | Background. Mycoplasmas are known to cause various infections in humans, mainly in the respiratory and urogenital tracts. The different species are usually host-specific and cause diseases in well-defined sites. New species have been isolated, including those from HIV-infected persons. Summary. Its in vitro properties, combined with clinical findings, have led to the hypothesis that these microorganisms may act as cofactors of HIV in AIDS development. Even today this point of view is quite polemic among infectious disease specialists and many aspects remain to be clarified, in contrast to what happens, for instance, with HIV/Mycobacterium tuberculosis coinfection. Dozens of papers have been published covering aspects of Mollicutes/HIV coinfection, but they add little to no information about the putative contribution of Mollicutes to the evolution of AIDS. Very few researchers have devoted their efforts to trying to answer this question, which remains open. In this review, we discuss the evidences that may support this statement in the light of current knowledge in the field of mycoplasmology. |
format | Article |
id | doaj-art-fa46a8f5c10f4260b8f5c6bff9bae3a7 |
institution | Kabale University |
issn | 1712-9532 1918-1493 |
language | English |
publishDate | 2016-01-01 |
publisher | Wiley |
record_format | Article |
series | Canadian Journal of Infectious Diseases and Medical Microbiology |
spelling | doaj-art-fa46a8f5c10f4260b8f5c6bff9bae3a72025-02-03T05:48:00ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95321918-14932016-01-01201610.1155/2016/81923238192323Mollicutes/HIV Coinfection and the Development of AIDS: Still Far from a Definitive ResponseCaio Mauricio Mendes de Cordova0Caroline Galgowski1Leonardo Lange2Department of Pharmaceutical Sciences, University of Blumenau, 89010-350 Blumenau, SC, BrazilBiomedical Sciences School, University of Blumenau, 89010-350 Blumenau, SC, BrazilBiomedical Sciences School, University of Blumenau, 89010-350 Blumenau, SC, BrazilBackground. Mycoplasmas are known to cause various infections in humans, mainly in the respiratory and urogenital tracts. The different species are usually host-specific and cause diseases in well-defined sites. New species have been isolated, including those from HIV-infected persons. Summary. Its in vitro properties, combined with clinical findings, have led to the hypothesis that these microorganisms may act as cofactors of HIV in AIDS development. Even today this point of view is quite polemic among infectious disease specialists and many aspects remain to be clarified, in contrast to what happens, for instance, with HIV/Mycobacterium tuberculosis coinfection. Dozens of papers have been published covering aspects of Mollicutes/HIV coinfection, but they add little to no information about the putative contribution of Mollicutes to the evolution of AIDS. Very few researchers have devoted their efforts to trying to answer this question, which remains open. In this review, we discuss the evidences that may support this statement in the light of current knowledge in the field of mycoplasmology.http://dx.doi.org/10.1155/2016/8192323 |
spellingShingle | Caio Mauricio Mendes de Cordova Caroline Galgowski Leonardo Lange Mollicutes/HIV Coinfection and the Development of AIDS: Still Far from a Definitive Response Canadian Journal of Infectious Diseases and Medical Microbiology |
title | Mollicutes/HIV Coinfection and the Development of AIDS: Still Far from a Definitive Response |
title_full | Mollicutes/HIV Coinfection and the Development of AIDS: Still Far from a Definitive Response |
title_fullStr | Mollicutes/HIV Coinfection and the Development of AIDS: Still Far from a Definitive Response |
title_full_unstemmed | Mollicutes/HIV Coinfection and the Development of AIDS: Still Far from a Definitive Response |
title_short | Mollicutes/HIV Coinfection and the Development of AIDS: Still Far from a Definitive Response |
title_sort | mollicutes hiv coinfection and the development of aids still far from a definitive response |
url | http://dx.doi.org/10.1155/2016/8192323 |
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