Primary subglottic inverted papilloma: An exceptional localization

Inverted papillomas are predominantly seen in the sinonasal region. Extra-sinonasal lesions are considered to be heterotopic. We present a case of primary laryngeal inverted papilloma with an unusual subglottic localization. An 84-year-old female patient presented with dyspnea on exertion. In the en...

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Main Authors: Özlem Saraydaroglu, Hakkı Caner İnan, Selin Yirmibes
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-12-01
Series:Indian Journal of Pathology and Microbiology
Subjects:
Online Access:https://journals.lww.com/10.4103/ijpm.ijpm_332_23
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author Özlem Saraydaroglu
Hakkı Caner İnan
Selin Yirmibes
author_facet Özlem Saraydaroglu
Hakkı Caner İnan
Selin Yirmibes
author_sort Özlem Saraydaroglu
collection DOAJ
description Inverted papillomas are predominantly seen in the sinonasal region. Extra-sinonasal lesions are considered to be heterotopic. We present a case of primary laryngeal inverted papilloma with an unusual subglottic localization. An 84-year-old female patient presented with dyspnea on exertion. In the endoscopic examination, a subglottic vegetative lesion was observed. Radiological examination revealed a well-circumscribed, solid mass involving the anterior commissure and extending to the subglottic region. Total excision of the mass was performed with the CO2 laser surgery. Histopathologic examination revealed endophytic growth of round-oval nests of transitional hyperplastic epithelium. The patient was diagnosed with primary laryngeal inverted papilloma. Primary laryngeal inverted papillomas are extremely rare. This is the fifth case and the only the second with a subglottic localization. Due to its rarity, it is difficult to predict the underlying cause and clinical course. However, cases with an atypical localization must be followed up like those in the sinonasal region.
format Article
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institution Kabale University
issn 0377-4929
0974-5130
language English
publishDate 2024-12-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Indian Journal of Pathology and Microbiology
spelling doaj-art-fa0426436495406dab4df9489167678b2025-01-10T10:26:26ZengWolters Kluwer Medknow PublicationsIndian Journal of Pathology and Microbiology0377-49290974-51302024-12-0167488488610.4103/ijpm.ijpm_332_23Primary subglottic inverted papilloma: An exceptional localizationÖzlem SaraydarogluHakkı Caner İnanSelin YirmibesInverted papillomas are predominantly seen in the sinonasal region. Extra-sinonasal lesions are considered to be heterotopic. We present a case of primary laryngeal inverted papilloma with an unusual subglottic localization. An 84-year-old female patient presented with dyspnea on exertion. In the endoscopic examination, a subglottic vegetative lesion was observed. Radiological examination revealed a well-circumscribed, solid mass involving the anterior commissure and extending to the subglottic region. Total excision of the mass was performed with the CO2 laser surgery. Histopathologic examination revealed endophytic growth of round-oval nests of transitional hyperplastic epithelium. The patient was diagnosed with primary laryngeal inverted papilloma. Primary laryngeal inverted papillomas are extremely rare. This is the fifth case and the only the second with a subglottic localization. Due to its rarity, it is difficult to predict the underlying cause and clinical course. However, cases with an atypical localization must be followed up like those in the sinonasal region.https://journals.lww.com/10.4103/ijpm.ijpm_332_23invertedlarynxpapillomasinonasalsubglottis
spellingShingle Özlem Saraydaroglu
Hakkı Caner İnan
Selin Yirmibes
Primary subglottic inverted papilloma: An exceptional localization
Indian Journal of Pathology and Microbiology
inverted
larynx
papilloma
sinonasal
subglottis
title Primary subglottic inverted papilloma: An exceptional localization
title_full Primary subglottic inverted papilloma: An exceptional localization
title_fullStr Primary subglottic inverted papilloma: An exceptional localization
title_full_unstemmed Primary subglottic inverted papilloma: An exceptional localization
title_short Primary subglottic inverted papilloma: An exceptional localization
title_sort primary subglottic inverted papilloma an exceptional localization
topic inverted
larynx
papilloma
sinonasal
subglottis
url https://journals.lww.com/10.4103/ijpm.ijpm_332_23
work_keys_str_mv AT ozlemsaraydaroglu primarysubglotticinvertedpapillomaanexceptionallocalization
AT hakkıcanerinan primarysubglotticinvertedpapillomaanexceptionallocalization
AT selinyirmibes primarysubglotticinvertedpapillomaanexceptionallocalization