A naked-eye biosensing system based on one-pot RPA-CRISPR/Cas12a driver G4-hemin self-assembly for Mycobacterium tuberculosis

A naked-eye biosensing system based on one-pot RPA-CRISPR/Cas12a driver G4-hemin self-assembly for Mycobacterium tuberculosis

IntroductionThe rapid and accurate identification of Mycobacterium tuberculosis (MTB) is essential for effective tuberculosis (TB) control. However, conventional diagnostic methods for MTB suffer from limitations such as low sensitivity, poor specificity, high cost, reliance on specialized instrumen...

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Bibliographic Details
Main Authors: Ting Yuan, Jianbo Yuan, Jian Huang, Nana Li, Huan Cai, Yan Yang, Juan Li, Rui Chen, Xun Min
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Chemistry
Subjects:
RPA-CRISPR/Cas12a
G4-hemin DNAzyme
naked-eye biosensing system
one-pot
Mycobacterium tuberculosis
Online Access:https://www.frontiersin.org/articles/10.3389/fchem.2025.1631086/full
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