Gold Nanoparticles: Multifunctional Properties, Synthesis, and Future Prospects

Gold nanoparticles (NPs) are among the most commonly employed metal NPs in biological applications, with distinctive physicochemical features. Their extraordinary optical properties, stemming from strong localized surface plasmon resonance (LSPR), contribute to the development of novel approaches in...

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Main Authors: Hatice Duman, Emir Akdaşçi, Furkan Eker, Mikhael Bechelany, Sercan Karav
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/14/22/1805
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author Hatice Duman
Emir Akdaşçi
Furkan Eker
Mikhael Bechelany
Sercan Karav
author_facet Hatice Duman
Emir Akdaşçi
Furkan Eker
Mikhael Bechelany
Sercan Karav
author_sort Hatice Duman
collection DOAJ
description Gold nanoparticles (NPs) are among the most commonly employed metal NPs in biological applications, with distinctive physicochemical features. Their extraordinary optical properties, stemming from strong localized surface plasmon resonance (LSPR), contribute to the development of novel approaches in the areas of bioimaging, biosensing, and cancer research, especially for photothermal and photodynamic therapy. The ease of functionalization with various ligands provides a novel approach to the precise delivery of these molecules to targeted areas. Gold NPs’ ability to transfer heat and electricity positions them as valuable materials for advancing thermal management and electronic systems. Moreover, their inherent characteristics, such as inertness, give rise to the synthesis of novel antibacterial and antioxidant agents as they provide a biocompatible and low-toxicity approach. Chemical and physical synthesis methods are utilized to produce gold NPs. The pursuit of more ecologically sustainable and economically viable large-scale technologies, such as environmentally benign biological processes referred to as green/biological synthesis, has garnered increasing interest among global researchers. Green synthesis methods are more favorable than other synthesis techniques as they minimize the necessity for hazardous chemicals in the reduction process due to their simplicity, cost-effectiveness, energy efficiency, and biocompatibility. This article discusses the importance of gold NPs, their optical, conductivity, antibacterial, antioxidant, and anticancer properties, synthesis methods, contemporary uses, and biosafety, emphasizing the need to understand toxicology principles and green commercialization strategies.
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spelling doaj-art-f9aa3d19234b4650a7a241a6098908a12024-11-26T18:16:24ZengMDPI AGNanomaterials2079-49912024-11-011422180510.3390/nano14221805Gold Nanoparticles: Multifunctional Properties, Synthesis, and Future ProspectsHatice Duman0Emir Akdaşçi1Furkan Eker2Mikhael Bechelany3Sercan Karav4Department of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17100, TürkiyeDepartment of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17100, TürkiyeDepartment of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17100, TürkiyeInstitut Européen des Membranes (IEM), UMR 5635, University Montpellier, ENSCM, CNRS, F-34095 Montpellier, FranceDepartment of Molecular Biology and Genetics, Çanakkale Onsekiz Mart University, Çanakkale 17100, TürkiyeGold nanoparticles (NPs) are among the most commonly employed metal NPs in biological applications, with distinctive physicochemical features. Their extraordinary optical properties, stemming from strong localized surface plasmon resonance (LSPR), contribute to the development of novel approaches in the areas of bioimaging, biosensing, and cancer research, especially for photothermal and photodynamic therapy. The ease of functionalization with various ligands provides a novel approach to the precise delivery of these molecules to targeted areas. Gold NPs’ ability to transfer heat and electricity positions them as valuable materials for advancing thermal management and electronic systems. Moreover, their inherent characteristics, such as inertness, give rise to the synthesis of novel antibacterial and antioxidant agents as they provide a biocompatible and low-toxicity approach. Chemical and physical synthesis methods are utilized to produce gold NPs. The pursuit of more ecologically sustainable and economically viable large-scale technologies, such as environmentally benign biological processes referred to as green/biological synthesis, has garnered increasing interest among global researchers. Green synthesis methods are more favorable than other synthesis techniques as they minimize the necessity for hazardous chemicals in the reduction process due to their simplicity, cost-effectiveness, energy efficiency, and biocompatibility. This article discusses the importance of gold NPs, their optical, conductivity, antibacterial, antioxidant, and anticancer properties, synthesis methods, contemporary uses, and biosafety, emphasizing the need to understand toxicology principles and green commercialization strategies.https://www.mdpi.com/2079-4991/14/22/1805gold nanoparticlesgreen synthesischemical and physical synthesisoptical propertydeliverysurface functionalization
spellingShingle Hatice Duman
Emir Akdaşçi
Furkan Eker
Mikhael Bechelany
Sercan Karav
Gold Nanoparticles: Multifunctional Properties, Synthesis, and Future Prospects
Nanomaterials
gold nanoparticles
green synthesis
chemical and physical synthesis
optical property
delivery
surface functionalization
title Gold Nanoparticles: Multifunctional Properties, Synthesis, and Future Prospects
title_full Gold Nanoparticles: Multifunctional Properties, Synthesis, and Future Prospects
title_fullStr Gold Nanoparticles: Multifunctional Properties, Synthesis, and Future Prospects
title_full_unstemmed Gold Nanoparticles: Multifunctional Properties, Synthesis, and Future Prospects
title_short Gold Nanoparticles: Multifunctional Properties, Synthesis, and Future Prospects
title_sort gold nanoparticles multifunctional properties synthesis and future prospects
topic gold nanoparticles
green synthesis
chemical and physical synthesis
optical property
delivery
surface functionalization
url https://www.mdpi.com/2079-4991/14/22/1805
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AT emirakdasci goldnanoparticlesmultifunctionalpropertiessynthesisandfutureprospects
AT furkaneker goldnanoparticlesmultifunctionalpropertiessynthesisandfutureprospects
AT mikhaelbechelany goldnanoparticlesmultifunctionalpropertiessynthesisandfutureprospects
AT sercankarav goldnanoparticlesmultifunctionalpropertiessynthesisandfutureprospects