Peripartum cardiomyopathy: current state of the problem
Peripartum cardiomyopathy (PCMP) is cardiomyo-pathy with left ventricular systolic dysfunction that develops in late pregnancy or in the first months of postpartum period. Clinical manifestations can vary from mild or moderate to severe symptoms of heart failure with significant functional limitatio...
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| Format: | Article |
| Language: | English |
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Zaslavsky O.Yu.
2024-11-01
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| Series: | Медицина неотложных состояний |
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| Online Access: | https://emergency.zaslavsky.com.ua/index.php/journal/article/view/1772 |
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| author | Ya.M. Lutai |
| author_facet | Ya.M. Lutai |
| author_sort | Ya.M. Lutai |
| collection | DOAJ |
| description | Peripartum cardiomyopathy (PCMP) is cardiomyo-pathy with left ventricular systolic dysfunction that develops in late pregnancy or in the first months of postpartum period. Clinical manifestations can vary from mild or moderate to severe symptoms of heart failure with significant functional limitation and high mortality. PCMP has a rather heterogeneous and incompletely studied pathophysiology, which includes hormonal, vascular, metabolic, and immunological pathways, whose implementation becomes possible on the background of genetic predisposition. Treatment is based on heart failure therapy, taking into account the risks associated with pregnancy and lactation. Bromocriptine is being considered as a specific therapy; however, the level of evidence for such treatment is insufficient. The article covers basic information about the pathophysiology, diagnosis, prognosis, prevention and treatment of PCMP at the current stage. For writing this review, the literature search was conducted using the MEDLINE, Scopus, and Web of Science databases. |
| format | Article |
| id | doaj-art-f9a91c96d8b24c929816a77735122c39 |
| institution | Kabale University |
| issn | 2224-0586 2307-1230 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Zaslavsky O.Yu. |
| record_format | Article |
| series | Медицина неотложных состояний |
| spelling | doaj-art-f9a91c96d8b24c929816a77735122c392025-01-12T11:41:05ZengZaslavsky O.Yu.Медицина неотложных состояний2224-05862307-12302024-11-0120754455310.22141/2224-0586.20.7.2024.17721772Peripartum cardiomyopathy: current state of the problemYa.M. Lutai0https://orcid.org/0000-0002-1776-8003State Institution “National Scientific Center “M.D. Strazhesko Institute of Cardiology, Clinical and Regeneration Medicine of the National Academy of Medical Sciences of Ukraine”, Kyiv, UkrainePeripartum cardiomyopathy (PCMP) is cardiomyo-pathy with left ventricular systolic dysfunction that develops in late pregnancy or in the first months of postpartum period. Clinical manifestations can vary from mild or moderate to severe symptoms of heart failure with significant functional limitation and high mortality. PCMP has a rather heterogeneous and incompletely studied pathophysiology, which includes hormonal, vascular, metabolic, and immunological pathways, whose implementation becomes possible on the background of genetic predisposition. Treatment is based on heart failure therapy, taking into account the risks associated with pregnancy and lactation. Bromocriptine is being considered as a specific therapy; however, the level of evidence for such treatment is insufficient. The article covers basic information about the pathophysiology, diagnosis, prognosis, prevention and treatment of PCMP at the current stage. For writing this review, the literature search was conducted using the MEDLINE, Scopus, and Web of Science databases.https://emergency.zaslavsky.com.ua/index.php/journal/article/view/1772peripartum cardiomyopathydiagnosistreatmentreview |
| spellingShingle | Ya.M. Lutai Peripartum cardiomyopathy: current state of the problem Медицина неотложных состояний peripartum cardiomyopathy diagnosis treatment review |
| title | Peripartum cardiomyopathy: current state of the problem |
| title_full | Peripartum cardiomyopathy: current state of the problem |
| title_fullStr | Peripartum cardiomyopathy: current state of the problem |
| title_full_unstemmed | Peripartum cardiomyopathy: current state of the problem |
| title_short | Peripartum cardiomyopathy: current state of the problem |
| title_sort | peripartum cardiomyopathy current state of the problem |
| topic | peripartum cardiomyopathy diagnosis treatment review |
| url | https://emergency.zaslavsky.com.ua/index.php/journal/article/view/1772 |
| work_keys_str_mv | AT yamlutai peripartumcardiomyopathycurrentstateoftheproblem |