Application of targeted metagenomic next-generation sequencing in pneumonia patients

Application of targeted metagenomic next-generation sequencing in pneumonia patients

ABSTRACT After the coronavirus disease 2019 (COVID-19) pandemic, the incidence rate of mixed infections, especially in critically ill patients with severe pneumonia, increases due to the immunity gap and has also been proven to be associated with mortality, increasing the difficulty in accurate and...

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Main Authors: Guanjun Ren, Liyun Ma, Chunliang Yan, Qishan Xue, Huijuan Zhang, Wei Wang, Xiyan Ren, Yun Lei, Shaofei Li, Yafeng Liu, Qingyue Zheng, Shigang Wei, Yue Zhang, Xiao Wang
Format: Article
Language:English
Published: American Society for Microbiology 2025-08-01
Series:Microbiology Spectrum
Subjects:
targeted metagenomic next-generation sequencing
capture hybridization
multiplex PCR
pneumonia
mixed infections
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01713-24
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https://journals.asm.org/doi/10.1128/spectrum.01713-24

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