Mechanism exploration of di(2-ethylhexyl) phthalate (DEHP)-induced breast cancer via network toxicology and molecular docking analysis
Abstract Disease caused by plasticizers has received increasing attention. Di(2-ethylhexyl) phthalate (DEHP), one of the most widely exposed plasticizers, has been shown to be closely associated with the development of breast cancer (BRCA) in epidemiological studies, but the specific mechanistic tar...
Saved in:
| Main Authors: | Zhongcheng Wang, Yunwen Wang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-13201-1 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Mechanisms of DEHP in the prostate carcinogenesis: A comprehensive bioinformatics analysis
by: Biao Ran, et al.
Published: (2025-08-01) -
Differential Effects of Bisphenol A and Di (2-Ethylhexyl) Phthalate Exposure on Crestin and the Expression of Some Genes Related to Apoptosis and Inflammation in Zebrafish Embryos
by: Perihan Seda Ateş Kalkan, et al.
Published: (2021-06-01) -
Mechanistic insight into plasticizer di-(2-ethylhexyl) phthalate as an environmental hazard for abdominal aortic aneurysm: Evidence from in vitro and in vivo studies
by: Yicheng Wang, et al.
Published: (2025-09-01) -
Using network toxicology and molecular docking to identify core targets and pathways underlying tacrolimus-induced tremor in organ transplant recipients
by: Chao Liu, et al.
Published: (2025-07-01) -
Analyzing the potential targets and mechanisms of liver damage induced by acetyl tributyl citrate plasticizer using network toxicology, molecular docking and in vitro experiments
by: Dong-qun Guo, et al.
Published: (2025-07-01)