Application of rapid genotyping of Warfarin individualized pharmacogenetic variants in Warfarin therapy

Application of rapid genotyping of Warfarin individualized pharmacogenetic variants in Warfarin therapy

Abstract Warfarin is the most widely used oral anticoagulant in clinical practice. The cytochrome P450 2C9 (CYP2C9), vitamin K epoxide reductase complex 1 (VKORC1), and cytochrome P450 4F2 (CYP4F2) genotypes are associated with warfarin dose requirements in China. Accurate genotyping is vital for ob...

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Bibliographic Details
Main Authors: Defa Huang, Fangfang Xie, Shengpeng Xiao, Minyang Cai, Die Hu, Baodian Ling, Fangsheng Wang, Xuan Lin, Fangli Song, Qi Wang, Tianyu Zhong
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-80639-0
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