Efficacy and mechanism of cyprosulfamide in alleviating the phytotoxicity of clomazone residue on maize seedling

IntroductionThe residues of clomazone (Clo) can lead to phytotoxic symptoms such as foliar bleaching, reduced plant height, and decreased maize yields. Herbicide safener represent one of the most economically efficient strategies for mitigating herbicide-induced damage.MethodsIn this study, various...

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Main Authors: Lanlan Sun, Chen Zhang, Hongle Xu, Wangcang Su, Fei Xue, Qiuli Leng, Yujia Niu, Chuantao Lu, Renhai Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-12-01
Series:Frontiers in Plant Science
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Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2024.1512055/full
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author Lanlan Sun
Lanlan Sun
Lanlan Sun
Chen Zhang
Chen Zhang
Chen Zhang
Hongle Xu
Hongle Xu
Hongle Xu
Wangcang Su
Wangcang Su
Wangcang Su
Fei Xue
Fei Xue
Fei Xue
Qiuli Leng
Qiuli Leng
Qiuli Leng
Yujia Niu
Yujia Niu
Yujia Niu
Chuantao Lu
Chuantao Lu
Chuantao Lu
Renhai Wu
Renhai Wu
Renhai Wu
author_facet Lanlan Sun
Lanlan Sun
Lanlan Sun
Chen Zhang
Chen Zhang
Chen Zhang
Hongle Xu
Hongle Xu
Hongle Xu
Wangcang Su
Wangcang Su
Wangcang Su
Fei Xue
Fei Xue
Fei Xue
Qiuli Leng
Qiuli Leng
Qiuli Leng
Yujia Niu
Yujia Niu
Yujia Niu
Chuantao Lu
Chuantao Lu
Chuantao Lu
Renhai Wu
Renhai Wu
Renhai Wu
author_sort Lanlan Sun
collection DOAJ
description IntroductionThe residues of clomazone (Clo) can lead to phytotoxic symptoms such as foliar bleaching, reduced plant height, and decreased maize yields. Herbicide safener represent one of the most economically efficient strategies for mitigating herbicide-induced damage.MethodsIn this study, various seed treatments were implemented, including the immersion of maize seeds in water (CK), immersion in Cyprosulfamide (CSA), soil supplemented with clomazone (ClO) and CSA+ClO, evaluated physiological indicators, chlorophyll content, and qRT-PCR analyses of the maize plants were evaluated under the different treatments.Results and discussionThe objective of this study was to investigate the impact of CSA on mitigating residual damage caused by Clo on maize and elucidate its mechanism. Compared to the CK, treatment with Clo resulted in significant inhibition of maize plant height, fresh weight, chlorophyll content, and carotenoid levels by 19.0%, 29.9%, 92.5%, and 86.3% respectively. On the other hand, under CSA+Clo treatment, milder inhibition was observed with reductions of only 9.4% in plant height and 7.2% in fresh weight, as well as decreases of 35.7% and 21.8% respectively in chlorophyll and carotenoid contents. The findings revealed that the application of CSA effectively mitigated the inhibitory effects of Clo residues on maize plant height, fresh weight, carotenoids and chlorophyll content. Additionally, the combination of CSA and Clo reduced MDA levels by 13.4%, increased SOD activity by 9.7% and GST activity by 26.7%, while elevating GSSG content by 31.3% compared to Clo alone, ultimately mitigating oxidative damage in maize plants. qRT-PCR analysis showed that the expression of five P450 genes (CYP72A5, CYP81A4, CYP81Q32, CYP81A9, CYP81A36), nine GST genes (GST30, GST31, GSTIV, GSTVI, GST21, GST7, GST37, GST25, IN2-1), and two UGT genes (UGT76C2, UGT83A1) significantly high increased by 6.74-, 10.27-, 4.98-, 10.56-, 25.67-, 16.70-, 46.92-,7.53-, 5.10-, 238.82-, 143.50-, 4.58-, 31.51-, 39.3-, 4.20-, 10.47-fold after CSA+Clo treatment compared to that in the Clo treatment. The pre-treatment of CSA led to the upregulation of five P450 genes, nine GST genes, and two UGT genes, which may be associated with the metabolism of Clo in maize. Overall, this study suggests that CSA could be effectively mitigates Clo residual damage by up-regulating detoxification-related genes, enhancing chlorophyll content and activities of antioxidant enzymes.
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spelling doaj-art-f8f906e1113249d6a52ecb9e8c42cbf42024-12-20T05:10:16ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2024-12-011510.3389/fpls.2024.15120551512055Efficacy and mechanism of cyprosulfamide in alleviating the phytotoxicity of clomazone residue on maize seedlingLanlan Sun0Lanlan Sun1Lanlan Sun2Chen Zhang3Chen Zhang4Chen Zhang5Hongle Xu6Hongle Xu7Hongle Xu8Wangcang Su9Wangcang Su10Wangcang Su11Fei Xue12Fei Xue13Fei Xue14Qiuli Leng15Qiuli Leng16Qiuli Leng17Yujia Niu18Yujia Niu19Yujia Niu20Chuantao Lu21Chuantao Lu22Chuantao Lu23Renhai Wu24Renhai Wu25Renhai Wu26Institute of Plant Protection, Henan Academy of Agricultural Sciences, Zhengzhou, ChinaHenan Key Laboratory of Agricultural Pest Monitoring and Control, Zhengzhou, ChinaKey Laboratory for Integrated Crop Pests Management on Crops in Southern Region of North China, Zhengzhou, ChinaInstitute of Plant Protection, Henan Academy of Agricultural Sciences, Zhengzhou, ChinaHenan Key Laboratory of Agricultural Pest Monitoring and Control, Zhengzhou, ChinaKey Laboratory for Integrated Crop Pests Management on Crops in Southern Region of North China, Zhengzhou, ChinaInstitute of Plant Protection, Henan Academy of Agricultural Sciences, Zhengzhou, ChinaHenan Key Laboratory of Agricultural Pest Monitoring and Control, Zhengzhou, ChinaKey Laboratory for Integrated Crop Pests Management on Crops in Southern Region of North China, Zhengzhou, ChinaInstitute of Plant Protection, Henan Academy of Agricultural Sciences, Zhengzhou, ChinaHenan Key Laboratory of Agricultural Pest Monitoring and Control, Zhengzhou, ChinaKey Laboratory for Integrated Crop Pests Management on Crops in Southern Region of North China, Zhengzhou, ChinaInstitute of Plant Protection, Henan Academy of Agricultural Sciences, Zhengzhou, ChinaHenan Key Laboratory of Agricultural Pest Monitoring and Control, Zhengzhou, ChinaKey Laboratory for Integrated Crop Pests Management on Crops in Southern Region of North China, Zhengzhou, ChinaInstitute of Plant Protection, Henan Academy of Agricultural Sciences, Zhengzhou, ChinaHenan Key Laboratory of Agricultural Pest Monitoring and Control, Zhengzhou, ChinaKey Laboratory for Integrated Crop Pests Management on Crops in Southern Region of North China, Zhengzhou, ChinaInstitute of Plant Protection, Henan Academy of Agricultural Sciences, Zhengzhou, ChinaHenan Key Laboratory of Agricultural Pest Monitoring and Control, Zhengzhou, ChinaKey Laboratory for Integrated Crop Pests Management on Crops in Southern Region of North China, Zhengzhou, ChinaInstitute of Plant Protection, Henan Academy of Agricultural Sciences, Zhengzhou, ChinaHenan Key Laboratory of Agricultural Pest Monitoring and Control, Zhengzhou, ChinaKey Laboratory for Integrated Crop Pests Management on Crops in Southern Region of North China, Zhengzhou, ChinaInstitute of Plant Protection, Henan Academy of Agricultural Sciences, Zhengzhou, ChinaHenan Key Laboratory of Agricultural Pest Monitoring and Control, Zhengzhou, ChinaKey Laboratory for Integrated Crop Pests Management on Crops in Southern Region of North China, Zhengzhou, ChinaIntroductionThe residues of clomazone (Clo) can lead to phytotoxic symptoms such as foliar bleaching, reduced plant height, and decreased maize yields. Herbicide safener represent one of the most economically efficient strategies for mitigating herbicide-induced damage.MethodsIn this study, various seed treatments were implemented, including the immersion of maize seeds in water (CK), immersion in Cyprosulfamide (CSA), soil supplemented with clomazone (ClO) and CSA+ClO, evaluated physiological indicators, chlorophyll content, and qRT-PCR analyses of the maize plants were evaluated under the different treatments.Results and discussionThe objective of this study was to investigate the impact of CSA on mitigating residual damage caused by Clo on maize and elucidate its mechanism. Compared to the CK, treatment with Clo resulted in significant inhibition of maize plant height, fresh weight, chlorophyll content, and carotenoid levels by 19.0%, 29.9%, 92.5%, and 86.3% respectively. On the other hand, under CSA+Clo treatment, milder inhibition was observed with reductions of only 9.4% in plant height and 7.2% in fresh weight, as well as decreases of 35.7% and 21.8% respectively in chlorophyll and carotenoid contents. The findings revealed that the application of CSA effectively mitigated the inhibitory effects of Clo residues on maize plant height, fresh weight, carotenoids and chlorophyll content. Additionally, the combination of CSA and Clo reduced MDA levels by 13.4%, increased SOD activity by 9.7% and GST activity by 26.7%, while elevating GSSG content by 31.3% compared to Clo alone, ultimately mitigating oxidative damage in maize plants. qRT-PCR analysis showed that the expression of five P450 genes (CYP72A5, CYP81A4, CYP81Q32, CYP81A9, CYP81A36), nine GST genes (GST30, GST31, GSTIV, GSTVI, GST21, GST7, GST37, GST25, IN2-1), and two UGT genes (UGT76C2, UGT83A1) significantly high increased by 6.74-, 10.27-, 4.98-, 10.56-, 25.67-, 16.70-, 46.92-,7.53-, 5.10-, 238.82-, 143.50-, 4.58-, 31.51-, 39.3-, 4.20-, 10.47-fold after CSA+Clo treatment compared to that in the Clo treatment. The pre-treatment of CSA led to the upregulation of five P450 genes, nine GST genes, and two UGT genes, which may be associated with the metabolism of Clo in maize. Overall, this study suggests that CSA could be effectively mitigates Clo residual damage by up-regulating detoxification-related genes, enhancing chlorophyll content and activities of antioxidant enzymes.https://www.frontiersin.org/articles/10.3389/fpls.2024.1512055/fullantioxidationcarotenoidgene expressionClomazone residuephytotoxicity
spellingShingle Lanlan Sun
Lanlan Sun
Lanlan Sun
Chen Zhang
Chen Zhang
Chen Zhang
Hongle Xu
Hongle Xu
Hongle Xu
Wangcang Su
Wangcang Su
Wangcang Su
Fei Xue
Fei Xue
Fei Xue
Qiuli Leng
Qiuli Leng
Qiuli Leng
Yujia Niu
Yujia Niu
Yujia Niu
Chuantao Lu
Chuantao Lu
Chuantao Lu
Renhai Wu
Renhai Wu
Renhai Wu
Efficacy and mechanism of cyprosulfamide in alleviating the phytotoxicity of clomazone residue on maize seedling
Frontiers in Plant Science
antioxidation
carotenoid
gene expression
Clomazone residue
phytotoxicity
title Efficacy and mechanism of cyprosulfamide in alleviating the phytotoxicity of clomazone residue on maize seedling
title_full Efficacy and mechanism of cyprosulfamide in alleviating the phytotoxicity of clomazone residue on maize seedling
title_fullStr Efficacy and mechanism of cyprosulfamide in alleviating the phytotoxicity of clomazone residue on maize seedling
title_full_unstemmed Efficacy and mechanism of cyprosulfamide in alleviating the phytotoxicity of clomazone residue on maize seedling
title_short Efficacy and mechanism of cyprosulfamide in alleviating the phytotoxicity of clomazone residue on maize seedling
title_sort efficacy and mechanism of cyprosulfamide in alleviating the phytotoxicity of clomazone residue on maize seedling
topic antioxidation
carotenoid
gene expression
Clomazone residue
phytotoxicity
url https://www.frontiersin.org/articles/10.3389/fpls.2024.1512055/full
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