STRUCTURAL AND FUNCTIONAL CONDITION OF THE KNEE JOINT IN PATIENTS WITH MONOGONARTHROSIS IN THE STAGE OF EXACERBATION
The goal is to study the structural changes of the elements of the knee joint and their functional consequences in patients with monogonarthrosis of the 1st-2nd grade in the stage of exacerbation according to the data of a complex clinical and arthroscopic study. Materials and Methods. Materials...
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Danylo Halytsky Lviv National Medical University
2022-06-01
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| Series: | Acta Medica Leopoliensia |
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| Online Access: | https://amljournal.com/index.php/journal/article/view/278 |
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| author | Taras Khanyk |
| author_facet | Taras Khanyk |
| author_sort | Taras Khanyk |
| collection | DOAJ |
| description | The goal is to study the structural changes of the elements of the knee joint and their functional consequences in patients with monogonarthrosis of the 1st-2nd grade in the stage of exacerbation according to the data of a complex clinical and arthroscopic study.
Materials and Methods. Materials - protocols of clinical, radiological and arthroscopic examination of 125 patients (54 (43.2%) men; 71 (57.8%) women), aged 18 - 79 years, with a previous diagnosis: Monoarthrosis of the knee joint in the stage of exacerbation. Research methods: questionnaire, orthopedic examination, X-ray diagnostics, arthroscopy, laboratory diagnostics of blood (determination of C-reactive protein (CRP) as a serological marker of inflammation), synovial fluid (analyses of physical properties, biochemical, cytological, bacteriological), statistical.
Results and Discussion. According to the results of the comprehensive examination, the presence of primary monoarthrosis was confirmed in 118 (94.4%) patients (group A). Based on the definition of CRP, subgroups were distinguished: A1 (n=71; 56.8%) with a normal level and A2 (n=47; 37.6%) with elevated CRP. In 7 (5.6%) patients diagnosed seropositive unspecified rheumatoid monoarthritis with hypertrophic synovitis (group B). A significant predominance of women compared to men insubgroup A2 was revealed (p<0.05). It was investigated that the features of complaints, nature of pain sensations and indicators of orthopedic status in patients from subgroups A1 and A2 did not reliably differ in groups of patients with different levels of CRP. A significant predominance of normal contours of the affected knee joint was found in subgroups A1 (p<0.001) and A2 (p<0.01). Structural changes in knee joint elements according to X-ray and arthroscopic examination have no significant differences in subgroups of patients A1 and A2.
Conclusions. The structural and functional state of the knee joints in patients with monogonarthrosis of the 1st-2nd grade according to the Kellgren-Lawrence classification is characterized by degenerative changes in almost all elements of the knee joint with moderate pain syndrome and functional disorders. |
| format | Article |
| id | doaj-art-f8ec74d167d045e3ad6e63ba08192a5b |
| institution | Kabale University |
| issn | 1029-4244 2415-3303 |
| language | English |
| publishDate | 2022-06-01 |
| publisher | Danylo Halytsky Lviv National Medical University |
| record_format | Article |
| series | Acta Medica Leopoliensia |
| spelling | doaj-art-f8ec74d167d045e3ad6e63ba08192a5b2025-01-06T10:49:52ZengDanylo Halytsky Lviv National Medical UniversityActa Medica Leopoliensia1029-42442415-33032022-06-01281-214716010.25040/aml2022.1-2.147278STRUCTURAL AND FUNCTIONAL CONDITION OF THE KNEE JOINT IN PATIENTS WITH MONOGONARTHROSIS IN THE STAGE OF EXACERBATIONTaras Khanyk0Kharkiv National Medical University, Kharkiv, UkraineThe goal is to study the structural changes of the elements of the knee joint and their functional consequences in patients with monogonarthrosis of the 1st-2nd grade in the stage of exacerbation according to the data of a complex clinical and arthroscopic study. Materials and Methods. Materials - protocols of clinical, radiological and arthroscopic examination of 125 patients (54 (43.2%) men; 71 (57.8%) women), aged 18 - 79 years, with a previous diagnosis: Monoarthrosis of the knee joint in the stage of exacerbation. Research methods: questionnaire, orthopedic examination, X-ray diagnostics, arthroscopy, laboratory diagnostics of blood (determination of C-reactive protein (CRP) as a serological marker of inflammation), synovial fluid (analyses of physical properties, biochemical, cytological, bacteriological), statistical. Results and Discussion. According to the results of the comprehensive examination, the presence of primary monoarthrosis was confirmed in 118 (94.4%) patients (group A). Based on the definition of CRP, subgroups were distinguished: A1 (n=71; 56.8%) with a normal level and A2 (n=47; 37.6%) with elevated CRP. In 7 (5.6%) patients diagnosed seropositive unspecified rheumatoid monoarthritis with hypertrophic synovitis (group B). A significant predominance of women compared to men insubgroup A2 was revealed (p<0.05). It was investigated that the features of complaints, nature of pain sensations and indicators of orthopedic status in patients from subgroups A1 and A2 did not reliably differ in groups of patients with different levels of CRP. A significant predominance of normal contours of the affected knee joint was found in subgroups A1 (p<0.001) and A2 (p<0.01). Structural changes in knee joint elements according to X-ray and arthroscopic examination have no significant differences in subgroups of patients A1 and A2. Conclusions. The structural and functional state of the knee joints in patients with monogonarthrosis of the 1st-2nd grade according to the Kellgren-Lawrence classification is characterized by degenerative changes in almost all elements of the knee joint with moderate pain syndrome and functional disorders.https://amljournal.com/index.php/journal/article/view/278monogonarthrosisstage of exacerbationclinical symptomsarthroscopystructural changes of the knee joint |
| spellingShingle | Taras Khanyk STRUCTURAL AND FUNCTIONAL CONDITION OF THE KNEE JOINT IN PATIENTS WITH MONOGONARTHROSIS IN THE STAGE OF EXACERBATION Acta Medica Leopoliensia monogonarthrosis stage of exacerbation clinical symptoms arthroscopy structural changes of the knee joint |
| title | STRUCTURAL AND FUNCTIONAL CONDITION OF THE KNEE JOINT IN PATIENTS WITH MONOGONARTHROSIS IN THE STAGE OF EXACERBATION |
| title_full | STRUCTURAL AND FUNCTIONAL CONDITION OF THE KNEE JOINT IN PATIENTS WITH MONOGONARTHROSIS IN THE STAGE OF EXACERBATION |
| title_fullStr | STRUCTURAL AND FUNCTIONAL CONDITION OF THE KNEE JOINT IN PATIENTS WITH MONOGONARTHROSIS IN THE STAGE OF EXACERBATION |
| title_full_unstemmed | STRUCTURAL AND FUNCTIONAL CONDITION OF THE KNEE JOINT IN PATIENTS WITH MONOGONARTHROSIS IN THE STAGE OF EXACERBATION |
| title_short | STRUCTURAL AND FUNCTIONAL CONDITION OF THE KNEE JOINT IN PATIENTS WITH MONOGONARTHROSIS IN THE STAGE OF EXACERBATION |
| title_sort | structural and functional condition of the knee joint in patients with monogonarthrosis in the stage of exacerbation |
| topic | monogonarthrosis stage of exacerbation clinical symptoms arthroscopy structural changes of the knee joint |
| url | https://amljournal.com/index.php/journal/article/view/278 |
| work_keys_str_mv | AT taraskhanyk structuralandfunctionalconditionofthekneejointinpatientswithmonogonarthrosisinthestageofexacerbation |