Deciphering hub genes and immune landscapes related to neutrophil extracellular traps in rheumatoid arthritis: insights from integrated bioinformatics analyses and experiments

Deciphering hub genes and immune landscapes related to neutrophil extracellular traps in rheumatoid arthritis: insights from integrated bioinformatics analyses and experiments

BackgroundRheumatoid arthritis (RA) is a chronic autoimmune disease characterized by synovial inflammation and progressive joint destruction. Neutrophil extracellular traps (NETs), a microreticular structure formed after neutrophil death, have recently been implicated in RA pathogenesis and patholog...

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Bibliographic Details
Main Authors: Yang Li, Jian Liu, Yue Sun, Yuedi Hu, Qiao Zhou, Chengzhi Cong, Yiming Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
rheumatoid arthritis
neutrophil extracellular traps
neutrophils
synovial microenvironment
inflammation
systems bioinformatics
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1521634/full
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