Chronic obstructive pulmonary disease (COPD): influence of clinic-anamnestic, anthropometric and functional characteristics on serum α-1-anitrypsin (AAT) in stable patients.
Aim of the study – to enhance the diagnostic and treatment tactics of stable COPD patients management at out patient stage by studying the serum AAT. Data of 45 outpatients with COPD (GOLD I-IV) and 20 healthy persons were included into analysis. Sex, age, height, weight, body mass index (BMI), smo...
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| Format: | Article |
| Language: | English |
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Dnipro State Medical University
2018-10-01
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| Series: | Medičnì Perspektivi |
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| Online Access: | http://journals.uran.ua/index.php/2307-0404/article/view/142334 |
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| author | K. Yu. Gashynova |
| author_facet | K. Yu. Gashynova |
| author_sort | K. Yu. Gashynova |
| collection | DOAJ |
| description | Aim of the study – to enhance the diagnostic and treatment tactics of stable COPD patients management at out patient stage by studying the serum AAT. Data of 45 outpatients with COPD (GOLD I-IV) and 20 healthy persons were included into analysis. Sex, age, height, weight, body mass index (BMI), smoking status were assessed. Lung function and serum AAT were measured. These results suggest that sex, age, height, weight, BMI do not influence on serum AAT both in stable COPD patients and healthy persons. Serum AAT statistically significant negatively correlate with airways obstruction degree in stable COPD patients. Significant moderate negative correlation between serum AAT and number of exacerbation during last year was found in stable COPD patients. This finding allows to suggest that serum AAT could be used as an indicator for COPD prognosis. |
| format | Article |
| id | doaj-art-f8c4fffc5c17429bb13b8c706f643e7f |
| institution | Kabale University |
| issn | 2307-0404 |
| language | English |
| publishDate | 2018-10-01 |
| publisher | Dnipro State Medical University |
| record_format | Article |
| series | Medičnì Perspektivi |
| spelling | doaj-art-f8c4fffc5c17429bb13b8c706f643e7f2025-01-02T01:46:12ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042018-10-01233(part1)526010.26641/2307-0404.2018.3(part1).142334142334Chronic obstructive pulmonary disease (COPD): influence of clinic-anamnestic, anthropometric and functional characteristics on serum α-1-anitrypsin (AAT) in stable patients.K. Yu. GashynovaAim of the study – to enhance the diagnostic and treatment tactics of stable COPD patients management at out patient stage by studying the serum AAT. Data of 45 outpatients with COPD (GOLD I-IV) and 20 healthy persons were included into analysis. Sex, age, height, weight, body mass index (BMI), smoking status were assessed. Lung function and serum AAT were measured. These results suggest that sex, age, height, weight, BMI do not influence on serum AAT both in stable COPD patients and healthy persons. Serum AAT statistically significant negatively correlate with airways obstruction degree in stable COPD patients. Significant moderate negative correlation between serum AAT and number of exacerbation during last year was found in stable COPD patients. This finding allows to suggest that serum AAT could be used as an indicator for COPD prognosis.http://journals.uran.ua/index.php/2307-0404/article/view/142334COPDexacerbationα-1-antitrypsin |
| spellingShingle | K. Yu. Gashynova Chronic obstructive pulmonary disease (COPD): influence of clinic-anamnestic, anthropometric and functional characteristics on serum α-1-anitrypsin (AAT) in stable patients. Medičnì Perspektivi COPD exacerbation α-1-antitrypsin |
| title | Chronic obstructive pulmonary disease (COPD): influence of clinic-anamnestic, anthropometric and functional characteristics on serum α-1-anitrypsin (AAT) in stable patients. |
| title_full | Chronic obstructive pulmonary disease (COPD): influence of clinic-anamnestic, anthropometric and functional characteristics on serum α-1-anitrypsin (AAT) in stable patients. |
| title_fullStr | Chronic obstructive pulmonary disease (COPD): influence of clinic-anamnestic, anthropometric and functional characteristics on serum α-1-anitrypsin (AAT) in stable patients. |
| title_full_unstemmed | Chronic obstructive pulmonary disease (COPD): influence of clinic-anamnestic, anthropometric and functional characteristics on serum α-1-anitrypsin (AAT) in stable patients. |
| title_short | Chronic obstructive pulmonary disease (COPD): influence of clinic-anamnestic, anthropometric and functional characteristics on serum α-1-anitrypsin (AAT) in stable patients. |
| title_sort | chronic obstructive pulmonary disease copd influence of clinic anamnestic anthropometric and functional characteristics on serum α 1 anitrypsin aat in stable patients |
| topic | COPD exacerbation α-1-antitrypsin |
| url | http://journals.uran.ua/index.php/2307-0404/article/view/142334 |
| work_keys_str_mv | AT kyugashynova chronicobstructivepulmonarydiseasecopdinfluenceofclinicanamnesticanthropometricandfunctionalcharacteristicsonseruma1anitrypsinaatinstablepatients |