LINC00525 drives aggressive phenotypes in bladder cancer via YAP stabilization-mediated transcriptional activation

LINC00525 drives aggressive phenotypes in bladder cancer via YAP stabilization-mediated transcriptional activation

Abstract LINC00525, a long noncoding RNA (lncRNA), has been implicated in the regulation of cancer progression across various types. However, its role in bladder cancer (BLCA) remains unconfirmed. In this study, we observed upregulation of LINC00525 expression in both bladder cancer tissues and cell...

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Bibliographic Details
Main Authors: Jiaming Liang, Shuyue Guo, Youzhi Wang, Qian Cao, Tao Guo, Diansheng Zhou, Junbo Li, Yihao Liao, Boqiang Zhong, Ning Jiang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Cancer Cell International
Subjects:
YAP
LncRNA
Ubiquitination
Bladder cancer
Online Access:https://doi.org/10.1186/s12935-025-03851-6
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