Reactive Lesions of the Oral Mucosa: A Retrospective Analysis of 69 Cases

Introduction: Reactive lesions encompass a category of fibroepithelial lesions that are frequently observed in the oral mucosa. Due to the oral cavity’s significant exposure to trauma or frictional forces, the incidence of these reactive lesions is notably higher within this anatomical region. Despi...

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Main Authors: Vaddadi Sindhuja, Vipparthi Sharon Raj, Divya Uppala
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2024-12-01
Series:Journal of Craniomaxillofacial Research
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Online Access:https://jcr.tums.ac.ir/index.php/jcr/article/view/515
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author Vaddadi Sindhuja
Vipparthi Sharon Raj
Divya Uppala
author_facet Vaddadi Sindhuja
Vipparthi Sharon Raj
Divya Uppala
author_sort Vaddadi Sindhuja
collection DOAJ
description Introduction: Reactive lesions encompass a category of fibroepithelial lesions that are frequently observed in the oral mucosa. Due to the oral cavity’s significant exposure to trauma or frictional forces, the incidence of these reactive lesions is notably higher within this anatomical region. Despite resembling neoplastic proliferations clinically, proper knowledge about these lesions is crucial for accurate diagnosis. Materials and Methods: Clinical data of all the reactive lesions were collected retrospectively from the 5-year archives of the Oral Pathology Department, GITAM Dental College and Hospital, Visakhapatnam. A  comprehensive clinical and histopathological assessment was conducted for all Reactive lesions. The collected data comprised age, gender, dimensions, location, and histopathological diagnosis, systematically compared and organized into tabulated formats. Results: In our study, we found that (54%) were females, with a slight female prediction. The 1st most common reactive lesion observed in our study was fibroepithelial polyp (29.85%). The gingiva was the most affected site (38.8%), followed by the buccal mucosa (31.3%). Conclusion: Reactive lesions are more prevalent in the oral cavity. As they can mimic multiple conditions, the clinical assessment was aligned with the histopathological characteristics to facilitate precise diagnosis while also delving deeper into the etiological factors implicated. Oral reactive lesions like pyogenic granuloma with unknown etiological factors need to be justified to arrive at a proper diagnosis, as suggested by Daley et al. Keywords: Reactive lesions; Fibroma; Pyogenic granuloma; Peripheral giant cell granuloma.
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series Journal of Craniomaxillofacial Research
spelling doaj-art-f8914cdc6894464693cb844f8f3730882025-01-06T08:40:58ZengTehran University of Medical SciencesJournal of Craniomaxillofacial Research2345-54892345-62132024-12-01113Reactive Lesions of the Oral Mucosa: A Retrospective Analysis of 69 CasesVaddadi Sindhuja0Vipparthi Sharon Raj1Divya Uppala2Department of Oral and Maxillofacial Pathology and Microbiology and Forensic Odontology, GITAM Dental College and Hospital, Visakhapatnam, India.Department of Oral and Maxillofacial Pathology and Microbiology and Forensic Odontology, GITAM Dental College and Hospital, Visakhapatnam, India.Department of Oral and Maxillofacial Pathology and Microbiology and Forensic Odontology, GITAM Dental College and Hospital, Visakhapatnam, India.Introduction: Reactive lesions encompass a category of fibroepithelial lesions that are frequently observed in the oral mucosa. Due to the oral cavity’s significant exposure to trauma or frictional forces, the incidence of these reactive lesions is notably higher within this anatomical region. Despite resembling neoplastic proliferations clinically, proper knowledge about these lesions is crucial for accurate diagnosis. Materials and Methods: Clinical data of all the reactive lesions were collected retrospectively from the 5-year archives of the Oral Pathology Department, GITAM Dental College and Hospital, Visakhapatnam. A  comprehensive clinical and histopathological assessment was conducted for all Reactive lesions. The collected data comprised age, gender, dimensions, location, and histopathological diagnosis, systematically compared and organized into tabulated formats. Results: In our study, we found that (54%) were females, with a slight female prediction. The 1st most common reactive lesion observed in our study was fibroepithelial polyp (29.85%). The gingiva was the most affected site (38.8%), followed by the buccal mucosa (31.3%). Conclusion: Reactive lesions are more prevalent in the oral cavity. As they can mimic multiple conditions, the clinical assessment was aligned with the histopathological characteristics to facilitate precise diagnosis while also delving deeper into the etiological factors implicated. Oral reactive lesions like pyogenic granuloma with unknown etiological factors need to be justified to arrive at a proper diagnosis, as suggested by Daley et al. Keywords: Reactive lesions; Fibroma; Pyogenic granuloma; Peripheral giant cell granuloma. https://jcr.tums.ac.ir/index.php/jcr/article/view/515Reactive lesions; Fibroma; Pyogenic granuloma; Peripheral giant cell granuloma.
spellingShingle Vaddadi Sindhuja
Vipparthi Sharon Raj
Divya Uppala
Reactive Lesions of the Oral Mucosa: A Retrospective Analysis of 69 Cases
Journal of Craniomaxillofacial Research
Reactive lesions; Fibroma; Pyogenic granuloma; Peripheral giant cell granuloma.
title Reactive Lesions of the Oral Mucosa: A Retrospective Analysis of 69 Cases
title_full Reactive Lesions of the Oral Mucosa: A Retrospective Analysis of 69 Cases
title_fullStr Reactive Lesions of the Oral Mucosa: A Retrospective Analysis of 69 Cases
title_full_unstemmed Reactive Lesions of the Oral Mucosa: A Retrospective Analysis of 69 Cases
title_short Reactive Lesions of the Oral Mucosa: A Retrospective Analysis of 69 Cases
title_sort reactive lesions of the oral mucosa a retrospective analysis of 69 cases
topic Reactive lesions; Fibroma; Pyogenic granuloma; Peripheral giant cell granuloma.
url https://jcr.tums.ac.ir/index.php/jcr/article/view/515
work_keys_str_mv AT vaddadisindhuja reactivelesionsoftheoralmucosaaretrospectiveanalysisof69cases
AT vipparthisharonraj reactivelesionsoftheoralmucosaaretrospectiveanalysisof69cases
AT divyauppala reactivelesionsoftheoralmucosaaretrospectiveanalysisof69cases