Induction of Cure in Early Arthritis (I CEA): study protocol for an investigator-initiated randomized single-blind clinical trial with open-label extension to compare three treatment strategies in patients with newly diagnosed undifferentiated arthritis

Induction of Cure in Early Arthritis (I CEA): study protocol for an investigator-initiated randomized single-blind clinical trial with open-label extension to compare three treatment strategies in patients with newly diagnosed undifferentiated arthritis

Abstract Background Undifferentiated arthritis (UA) is a term used to describe patients with inflammatory arthritis that has not differentiated into a specific rheumatic disease. UA may be a pre-stage of rheumatoid arthritis (RA) or another inflammatory disease or remain undifferentiated, but a subs...

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Bibliographic Details
Main Authors: S. A. Bergstra, L. van Ouwerkerk, I. S. Nevins, J. A. van der Pol, G. S. Helmich, I. Hest, A. van Veen, R. Bos, Y. P. M. Goekoop-Ruiterman, H. E. Vonkeman, J. Bijsterbosch, P. H. P. de Jong, M. Güler-Yüksel, S. Böhringer, T. W. J. Huizinga, F. A. van Gaalen
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Trials
Subjects:
Undifferentiated arthritis
Spontaneous remission
NSAID
Methotrexate
Baricitinib
Randomized
Online Access:https://doi.org/10.1186/s13063-024-08609-5
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