DNA Methylation Pattern and mRNA Expression Level of E-Cadherin and P16 Genes in Thrombotic Disorders

DNA Methylation Pattern and mRNA Expression Level of E-Cadherin and P16 Genes in Thrombotic Disorders

Objective DNA methylation, as an epigenetic alteration, plays an essential role in the development of atherosclerosis and venous thrombosis. E-cadherin, a tumor suppressor gene and adhesion molecule, has a crucial function in platelet aggregation and hemostasis. P16, a cell cycle regulator, is invol...

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Bibliographic Details
Main Authors: Niloofar Abak M.Sc, Mehdi Azad Ph.D, Fatemeh Mohammad Ali Ph.D, Mostafa Saberian Ph.D, Saeed Turkaman M.Sc, Shaban Alizadeh Prof
Format: Article
Language:English
Published: SAGE Publishing 2024-12-01
Series:Clinical and Applied Thrombosis/Hemostasis
Online Access:https://doi.org/10.1177/10760296241300490
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