Synergistic increase in coproporphyrin III biosynthesis by mitochondrial compartmentalization in engineered Saccharomyces cerevisiae

Synergistic increase in coproporphyrin III biosynthesis by mitochondrial compartmentalization in engineered Saccharomyces cerevisiae

Coproporphyrin III (CP III), a natural porphyrin derivative, has extensive applications in the biomedical and material industries. S. cerevisiae has previously been engineered to highly accumulate the CP III precursor 5-aminolevulinic acid (ALA) through the C4 pathway. In this study, a combination o...

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Bibliographic Details
Main Authors: Qidi Guo, Jiaqi Xu, Jiacun Li, Shuyan Tang, Yuhui Cheng, Bei Gao, Liang-Bin Xiong, Jie Xiong, Feng-Qing Wang, Dong-Zhi Wei
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-12-01
Series:Synthetic and Systems Biotechnology
Subjects:
Coproporphyrin III
Saccharomyces cerevisiae
Mitochondrial compartmentalization
Anti-oxidation
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X24000991
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