Non-collapsibility and built-in selection bias of period-specific and conventional hazard ratio in randomized controlled trials
Abstract Background The hazard ratio of the Cox proportional hazards model is widely used in randomized controlled trials to assess treatment effects. However, two properties of the hazard ratio including the non-collapsibility and built-in selection bias need to be further investigated. Methods We...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2024-11-01
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| Series: | BMC Medical Research Methodology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12874-024-02402-3 |
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