Circulating HBsAg-specific B cells are partially rescued in chronically HBV-infected patients with functional cure

Circulating HBsAg-specific B cells are partially rescued in chronically HBV-infected patients with functional cure

It is well established that humoral immunity targeting hepatitis B virus surface antigen (HBsAg) plays a critical role in viral clearance and clinical cure. However, the functional changes in HBsAg-specific B cells before and after achieving functional cure remain poorly understood. In this study, w...

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Bibliographic Details
Main Authors: Shuqin Gu, Libo Tang, Ling Guo, Chunxiu Zhong, Xin Fu, Guofu Ye, Shihong Zhong, Xiaoyi Li, Chunhua Wen, Yang Zhou, Jinling Wei, Haitao Chen, Nikolai Novikov, Simon P. Fletcher, M. Anthony Moody, Jinlin Hou, Yongyin Li
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Emerging Microbes and Infections
Subjects:
Hepatitis B surface antigen
B cells
hepatitis B surface antigen clearance
functional cure
B-cell epitope
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2024.2409350
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