Microneedle patches incorporating zinc-doped mesoporous silica nanoparticles loaded with betamethasone dipropionate for psoriasis treatment

Microneedle patches incorporating zinc-doped mesoporous silica nanoparticles loaded with betamethasone dipropionate for psoriasis treatment

Abstract Treating psoriasis presents a major clinical challenge because of the limitations associated with traditional topical glucocorticoid therapy. This study introduced a drug delivery system utilizing zinc-doped mesoporous silica nanoparticle (Zn-MSN) and microneedle (MN), designed to enhance d...

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Bibliographic Details
Main Authors: Jun Li, Zhiguo Yuan, Shuyu Shi, Xingtao Chen, Shuangshuang Yu, Xiaoshu Qi, Tong Deng, Yifei Zhou, Dan Tang, Saihong Xu, Jue Zhang, Yingfu Jiao, Weifeng Yu, Liya Wang, Liqun Yang, Po Gao
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Nanobiotechnology
Subjects:
Microneedle
Mesoporous silica nanoparticle
Psoriasis
Itch
Betamethasone dipropionate
Online Access:https://doi.org/10.1186/s12951-024-02986-4
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