Evaluating the Impact of Primary Tumor Resection on EGFR-TKI-treated Patients with Advanced Lung Cancer: A Multicenter Propensity-matched Study

Evaluating the Impact of Primary Tumor Resection on EGFR-TKI-treated Patients with Advanced Lung Cancer: A Multicenter Propensity-matched Study

Background: Nonsmall-cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) mutations is exceptionally sensitive to EGFR tyrosine kinase inhibitors (TKIs). Despite this, disease progression commonly occurs at the primary site, prompting debate on the potential advantages of incorporat...

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Bibliographic Details
Main Authors: Eva Yu-Hsuan Chuang, Chiao-En Wu, Tzu-Wei Kuo, Yu-Wen Wen, Ping-Chih Hsu, Chih-Hsi Scott Kuo, Cheng-Ta Yang, Ling-Jen Hung, Yin-Kai Chao
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-04-01
Series:Journal of Cancer Research and Practice
Subjects:
epidermal growth factor receptor
local consolidation therapy
nonsmall-cell lung cancer
primary tumor resection
progression-free survival
tyrosine kinase inhibitors
Online Access:https://journals.lww.com/10.4103/ejcrp.eJCRP-D-24-00037
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