Incidence of clindamycin resistance in clinical isolates of Staphylococcus aureus
Clindamycin is used in Staphylococcal infections and resistance patterns to Clindamycin vary between institutions. Inducible Clindamycin resistance is detected by the CLSI recommended D-test. This study was done to estimate the incidence of constitutive and inducible Clindamycin resistance in our h...
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| Format: | Article |
| Language: | English |
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The Journal of Infection in Developing Countries
2011-03-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/1598 |
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| author | Debmita Debdas Sangeeta Joshi |
| author_facet | Debmita Debdas Sangeeta Joshi |
| author_sort | Debmita Debdas |
| collection | DOAJ |
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Clindamycin is used in Staphylococcal infections and resistance patterns to Clindamycin vary between institutions. Inducible Clindamycin resistance is detected by the CLSI recommended D-test. This study was done to estimate the incidence of constitutive and inducible Clindamycin resistance in our hospital. Three hundred and seventy nine S.aureus isolates from clinical specimens collected over 6 months were tested for Clindamycin resistance using the D-test. Fourteen percent were Clindamycin resistant and among them 43% showed the inducible phenotype. Clindamycin resistance was higher among MRSA isolates (p < 0.001). It was concluded that Clindamycin should not be used empirically in serious Staphylococcal infections and that such studies are necessary to guide empiric therapy.
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| format | Article |
| id | doaj-art-f73a510bf3d2419ca6900e55dd0e7d4c |
| institution | Kabale University |
| issn | 1972-2680 |
| language | English |
| publishDate | 2011-03-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-f73a510bf3d2419ca6900e55dd0e7d4c2025-08-20T03:48:58ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802011-03-0150410.3855/jidc.1598Incidence of clindamycin resistance in clinical isolates of Staphylococcus aureusDebmita Debdas0Sangeeta Joshi1Jyoti Laboratory, Assam Trunk Road, Jorhat - 785001, Assam, IndiaManipal Hospital, Airport Road, Bangalore – 560017, India Clindamycin is used in Staphylococcal infections and resistance patterns to Clindamycin vary between institutions. Inducible Clindamycin resistance is detected by the CLSI recommended D-test. This study was done to estimate the incidence of constitutive and inducible Clindamycin resistance in our hospital. Three hundred and seventy nine S.aureus isolates from clinical specimens collected over 6 months were tested for Clindamycin resistance using the D-test. Fourteen percent were Clindamycin resistant and among them 43% showed the inducible phenotype. Clindamycin resistance was higher among MRSA isolates (p < 0.001). It was concluded that Clindamycin should not be used empirically in serious Staphylococcal infections and that such studies are necessary to guide empiric therapy. https://jidc.org/index.php/journal/article/view/1598clindamycin resistanceStaphylococcus aureusD-test |
| spellingShingle | Debmita Debdas Sangeeta Joshi Incidence of clindamycin resistance in clinical isolates of Staphylococcus aureus Journal of Infection in Developing Countries clindamycin resistance Staphylococcus aureus D-test |
| title | Incidence of clindamycin resistance in clinical isolates of Staphylococcus aureus |
| title_full | Incidence of clindamycin resistance in clinical isolates of Staphylococcus aureus |
| title_fullStr | Incidence of clindamycin resistance in clinical isolates of Staphylococcus aureus |
| title_full_unstemmed | Incidence of clindamycin resistance in clinical isolates of Staphylococcus aureus |
| title_short | Incidence of clindamycin resistance in clinical isolates of Staphylococcus aureus |
| title_sort | incidence of clindamycin resistance in clinical isolates of staphylococcus aureus |
| topic | clindamycin resistance Staphylococcus aureus D-test |
| url | https://jidc.org/index.php/journal/article/view/1598 |
| work_keys_str_mv | AT debmitadebdas incidenceofclindamycinresistanceinclinicalisolatesofstaphylococcusaureus AT sangeetajoshi incidenceofclindamycinresistanceinclinicalisolatesofstaphylococcusaureus |