Can different formulae be used in the diagnosis and staging of chronic kidney disease?
Chronic kidney disease (CKD), which has a significant prevalence of 15.7 % in Turkey, is a global health problem that particularly affects elderly. It is difficult to distinguish between age-related and CKD-related declines in kidney function with current glomerular filtration rate (GFR) estimation...
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| Format: | Article |
| Language: | English |
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De Gruyter
2024-10-01
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| Series: | Türk Biyokimya Dergisi |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/tjb-2024-0008 |
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| _version_ | 1841536607457378304 |
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| author | Çam Ergin Kural Alev Yılmaz Mürvet |
| author_facet | Çam Ergin Kural Alev Yılmaz Mürvet |
| author_sort | Çam Ergin |
| collection | DOAJ |
| description | Chronic kidney disease (CKD), which has a significant prevalence of 15.7 % in Turkey, is a global health problem that particularly affects elderly. It is difficult to distinguish between age-related and CKD-related declines in kidney function with current glomerular filtration rate (GFR) estimation methods. The “HUGE” formula, incorporating haematocrit, urea, and gender, offers improved differentiation, targeting individuals over 40. This study aims to evaluate the effectiveness of the HUGE formula in estimating GFR in this demographic group and to establish a better diagnostic threshold. |
| format | Article |
| id | doaj-art-f725674dde2946689e0ddd42c16d2768 |
| institution | Kabale University |
| issn | 1303-829X |
| language | English |
| publishDate | 2024-10-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Türk Biyokimya Dergisi |
| spelling | doaj-art-f725674dde2946689e0ddd42c16d27682025-01-14T14:22:30ZengDe GruyterTürk Biyokimya Dergisi1303-829X2024-10-0149671072010.1515/tjb-2024-0008Can different formulae be used in the diagnosis and staging of chronic kidney disease?Çam Ergin0Kural Alev1Yılmaz Mürvet2Department of Clinical Chemistry, Department of Biochemistry, University of Health Sciences, Bakirköy Dr. Sadi Konuk Training and Research Hospital, İstanbul, TürkiyeDepartment of Clinical Chemistry, Department of Biochemistry, University of Health Sciences, Bakirköy Dr. Sadi Konuk Training and Research Hospital, İstanbul, TürkiyeDepartment of Nephrology, Department of Biochemistry, University of Health Sciences, Bakirköy Dr. Sadi Konuk Training and Research Hospital, İstanbul, TürkiyeChronic kidney disease (CKD), which has a significant prevalence of 15.7 % in Turkey, is a global health problem that particularly affects elderly. It is difficult to distinguish between age-related and CKD-related declines in kidney function with current glomerular filtration rate (GFR) estimation methods. The “HUGE” formula, incorporating haematocrit, urea, and gender, offers improved differentiation, targeting individuals over 40. This study aims to evaluate the effectiveness of the HUGE formula in estimating GFR in this demographic group and to establish a better diagnostic threshold.https://doi.org/10.1515/tjb-2024-0008chronic kidney diseaseestimated glomerular filtration ratehuge equationkdigo formulaereduced nephron function |
| spellingShingle | Çam Ergin Kural Alev Yılmaz Mürvet Can different formulae be used in the diagnosis and staging of chronic kidney disease? Türk Biyokimya Dergisi chronic kidney disease estimated glomerular filtration rate huge equation kdigo formulae reduced nephron function |
| title | Can different formulae be used in the diagnosis and staging of chronic kidney disease? |
| title_full | Can different formulae be used in the diagnosis and staging of chronic kidney disease? |
| title_fullStr | Can different formulae be used in the diagnosis and staging of chronic kidney disease? |
| title_full_unstemmed | Can different formulae be used in the diagnosis and staging of chronic kidney disease? |
| title_short | Can different formulae be used in the diagnosis and staging of chronic kidney disease? |
| title_sort | can different formulae be used in the diagnosis and staging of chronic kidney disease |
| topic | chronic kidney disease estimated glomerular filtration rate huge equation kdigo formulae reduced nephron function |
| url | https://doi.org/10.1515/tjb-2024-0008 |
| work_keys_str_mv | AT camergin candifferentformulaebeusedinthediagnosisandstagingofchronickidneydisease AT kuralalev candifferentformulaebeusedinthediagnosisandstagingofchronickidneydisease AT yılmazmurvet candifferentformulaebeusedinthediagnosisandstagingofchronickidneydisease |