Transcriptomic and Metabolomic Analysis Reveal the Effects of Light Quality on the Growth and Lipid Biosynthesis in <i>Chlorella pyrenoidosa</i>

Light quality has significant effects on the growth and metabolite accumulation of algal cells. However, the related mechanism has not been fully elucidated. This study reveals that both red and blue light can promote the growth and biomass accumulation of <i>Chlorella pyrenoidosa</i>, w...

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Main Authors: Tingting Zhu, Ge Guan, Lele Huang, Lina Wen, Linxuan Li, Maozhi Ren
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/14/9/1144
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author Tingting Zhu
Ge Guan
Lele Huang
Lina Wen
Linxuan Li
Maozhi Ren
author_facet Tingting Zhu
Ge Guan
Lele Huang
Lina Wen
Linxuan Li
Maozhi Ren
author_sort Tingting Zhu
collection DOAJ
description Light quality has significant effects on the growth and metabolite accumulation of algal cells. However, the related mechanism has not been fully elucidated. This study reveals that both red and blue light can promote the growth and biomass accumulation of <i>Chlorella pyrenoidosa</i>, with the enhancing effect of blue light being more pronounced. Cultivation under blue light reduced the content of total carbohydrate in <i>Chlorella pyrenoidosa</i>, while increasing the content of protein and lipid. Conversely, red light decreased the content of protein and increased the content of carbohydrate and lipid. Blue light induces a shift in carbon flux from carbohydrate to protein, while red light transfers carbon flux from protein to lipid. Transcriptomic and metabolomic analysis indicated that both red and blue light positively regulate lipid synthesis in <i>Chlorella pyrenoidosa</i>, but they exhibited distinct impacts on the fatty acid compositions. These findings suggest that manipulating light qualities can modulate carbon metabolic pathways, potentially converting protein into lipid in <i>Chlorella pyrenoidosa</i>.
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publishDate 2024-09-01
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series Biomolecules
spelling doaj-art-f70e423e426a44c788bf8cc3f8dd5df02025-08-20T01:56:05ZengMDPI AGBiomolecules2218-273X2024-09-01149114410.3390/biom14091144Transcriptomic and Metabolomic Analysis Reveal the Effects of Light Quality on the Growth and Lipid Biosynthesis in <i>Chlorella pyrenoidosa</i>Tingting Zhu0Ge Guan1Lele Huang2Lina Wen3Linxuan Li4Maozhi Ren5Institute of Urban Agriculture, Chinese Academy of Agricultural Sciences, Chengdu National Agricultural Science and Technology Center, Chengdu 610213, ChinaSchool of Agricultural Science, Zhengzhou University, Zhengzhou 450001, ChinaInstitute of Urban Agriculture, Chinese Academy of Agricultural Sciences, Chengdu National Agricultural Science and Technology Center, Chengdu 610213, ChinaSchool of Agricultural Science, Zhengzhou University, Zhengzhou 450001, ChinaInstitute of Urban Agriculture, Chinese Academy of Agricultural Sciences, Chengdu National Agricultural Science and Technology Center, Chengdu 610213, ChinaInstitute of Urban Agriculture, Chinese Academy of Agricultural Sciences, Chengdu National Agricultural Science and Technology Center, Chengdu 610213, ChinaLight quality has significant effects on the growth and metabolite accumulation of algal cells. However, the related mechanism has not been fully elucidated. This study reveals that both red and blue light can promote the growth and biomass accumulation of <i>Chlorella pyrenoidosa</i>, with the enhancing effect of blue light being more pronounced. Cultivation under blue light reduced the content of total carbohydrate in <i>Chlorella pyrenoidosa</i>, while increasing the content of protein and lipid. Conversely, red light decreased the content of protein and increased the content of carbohydrate and lipid. Blue light induces a shift in carbon flux from carbohydrate to protein, while red light transfers carbon flux from protein to lipid. Transcriptomic and metabolomic analysis indicated that both red and blue light positively regulate lipid synthesis in <i>Chlorella pyrenoidosa</i>, but they exhibited distinct impacts on the fatty acid compositions. These findings suggest that manipulating light qualities can modulate carbon metabolic pathways, potentially converting protein into lipid in <i>Chlorella pyrenoidosa</i>.https://www.mdpi.com/2218-273X/14/9/1144light qualitybiomasslipid biosynthesisomics analysis<i>Chlorella pyrenoidosa</i>
spellingShingle Tingting Zhu
Ge Guan
Lele Huang
Lina Wen
Linxuan Li
Maozhi Ren
Transcriptomic and Metabolomic Analysis Reveal the Effects of Light Quality on the Growth and Lipid Biosynthesis in <i>Chlorella pyrenoidosa</i>
Biomolecules
light quality
biomass
lipid biosynthesis
omics analysis
<i>Chlorella pyrenoidosa</i>
title Transcriptomic and Metabolomic Analysis Reveal the Effects of Light Quality on the Growth and Lipid Biosynthesis in <i>Chlorella pyrenoidosa</i>
title_full Transcriptomic and Metabolomic Analysis Reveal the Effects of Light Quality on the Growth and Lipid Biosynthesis in <i>Chlorella pyrenoidosa</i>
title_fullStr Transcriptomic and Metabolomic Analysis Reveal the Effects of Light Quality on the Growth and Lipid Biosynthesis in <i>Chlorella pyrenoidosa</i>
title_full_unstemmed Transcriptomic and Metabolomic Analysis Reveal the Effects of Light Quality on the Growth and Lipid Biosynthesis in <i>Chlorella pyrenoidosa</i>
title_short Transcriptomic and Metabolomic Analysis Reveal the Effects of Light Quality on the Growth and Lipid Biosynthesis in <i>Chlorella pyrenoidosa</i>
title_sort transcriptomic and metabolomic analysis reveal the effects of light quality on the growth and lipid biosynthesis in i chlorella pyrenoidosa i
topic light quality
biomass
lipid biosynthesis
omics analysis
<i>Chlorella pyrenoidosa</i>
url https://www.mdpi.com/2218-273X/14/9/1144
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