Mendelian Randomisation: Concepts, Opportunities, Challenges, and Future Directions

Mendelian Randomisation: Concepts, Opportunities, Challenges, and Future Directions

Mendelian randomisation is an approach in genetic epidemiology that uses genetic variants as instrumental variables to investigate the causal relationship between genetically proxied exposures and health outcomes. During the last years, the number of published Mendelian randomisation studies increas...

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Bibliographic Details
Main Authors: Sophie C. de Ruiter, Lena Tschiderer, Diederick E. Grobbee, Peter Willeit, Hester M. den Ruijter, A. Floriaan Schmidt, Sanne A. E. Peters
Format: Article
Language:English
Published: Ubiquity Press 2025-06-01
Series:Global Heart
Subjects:
mendelian randomisation
opportunities
challenges
perspective
subgroups
sex-specific
omics
Online Access:https://account.globalheartjournal.com/index.php/up-j-gh/article/view/1438
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