Mitochondrial ROS and HIF-1α signaling mediate synaptic plasticity in the critical period.

Mitochondrial ROS and HIF-1α signaling mediate synaptic plasticity in the critical period.

As developing networks transition from spontaneous irregular to patterned activity, they undergo plastic tuning phases, termed "critical periods"; "critical" because disturbances during these phases can lead to lasting changes in network development and output. Critical periods a...

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Bibliographic Details
Main Authors: Daniel Sobrido-Cameán, Bramwell Coulson, Michael Miller, Matthew C W Oswald, Tom Pettini, David M D Bailey, Richard A Baines, Matthias Landgraf
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-08-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3003338
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