Evolving insights on the role of microglia in neuroinflammation, plasticity, and regeneration of the injured spinal cord

Evolving insights on the role of microglia in neuroinflammation, plasticity, and regeneration of the injured spinal cord

Microglia have emerged as central players in the pathophysiology of traumatic spinal cord injury (SCI). The purpose of this brief review is to highlight the evolution of knowledge on the role of microglia in SCI. We explore the initial discovery of macrophages and their role in SCI lesions, followed...

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Bibliographic Details
Main Authors: Emily A. Swarts, Faith H. Brennan
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Immunology
Subjects:
microglia
astrogliosis
neurotrauma
demyelination
axon regeneration
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1621789/full
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