Accurate Detection of scutellata‐Hybrids (Africanized Bees) Using a SNP‐Based Diagnostic Assay

ABSTRACT Hybrid populations of Africanized honey bees (scutellata‐hybrids), notable for their defensive behaviour, have spread rapidly throughout South and North America since their unintentional introduction. Although their migration has slowed, the large‐scale trade and movement of honey bee queen...

Full description

Saved in:
Bibliographic Details
Main Authors: Kathleen A. Dogantzis, Harshilkumar Patel, Stephen Rose, Ida M. Conflitti, Alivia Dey, Tanushree Tiwari, Nadine C. Chapman, Samir M. Kadri, Harland M. Patch, Elliud M. Muli, Abdulaziz S. Alqarni, Michael H. Allsopp, Amro Zayed
Format: Article
Language:English
Published: Wiley 2024-11-01
Series:Ecology and Evolution
Subjects:
Online Access:https://doi.org/10.1002/ece3.70554
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1846114991136047104
author Kathleen A. Dogantzis
Harshilkumar Patel
Stephen Rose
Ida M. Conflitti
Alivia Dey
Tanushree Tiwari
Nadine C. Chapman
Samir M. Kadri
Harland M. Patch
Elliud M. Muli
Abdulaziz S. Alqarni
Michael H. Allsopp
Amro Zayed
author_facet Kathleen A. Dogantzis
Harshilkumar Patel
Stephen Rose
Ida M. Conflitti
Alivia Dey
Tanushree Tiwari
Nadine C. Chapman
Samir M. Kadri
Harland M. Patch
Elliud M. Muli
Abdulaziz S. Alqarni
Michael H. Allsopp
Amro Zayed
author_sort Kathleen A. Dogantzis
collection DOAJ
description ABSTRACT Hybrid populations of Africanized honey bees (scutellata‐hybrids), notable for their defensive behaviour, have spread rapidly throughout South and North America since their unintentional introduction. Although their migration has slowed, the large‐scale trade and movement of honey bee queens and colonies raise concern over the accidental importation of scutellata‐hybrids to previously unoccupied areas. Therefore, developing an accurate and robust assay to detect scutellata‐hybrids is an important first step toward mitigating risk. Here, we used an extensive population genomic dataset to assess the genomic composition of Apis mellifera native populations and patterns of genetic admixture in North and South American commercial honey bees. We used this dataset to develop a SNP assay, where 80 markers, combined with machine learning classification, can accurately differentiate between scutellata‐hybrids and non‐scutellata‐hybrid commercial colonies. The assay was validated on 1263 individuals from colonies located in Canada, the United States, Australia and Brazil. Notably, we demonstrate that using a reduced SNP set of as few as 10 loci can still provide accurate results.
format Article
id doaj-art-f6912bcd55ec40dc8e125351efc149d0
institution Kabale University
issn 2045-7758
language English
publishDate 2024-11-01
publisher Wiley
record_format Article
series Ecology and Evolution
spelling doaj-art-f6912bcd55ec40dc8e125351efc149d02024-12-20T04:20:57ZengWileyEcology and Evolution2045-77582024-11-011411n/an/a10.1002/ece3.70554Accurate Detection of scutellata‐Hybrids (Africanized Bees) Using a SNP‐Based Diagnostic AssayKathleen A. Dogantzis0Harshilkumar Patel1Stephen Rose2Ida M. Conflitti3Alivia Dey4Tanushree Tiwari5Nadine C. Chapman6Samir M. Kadri7Harland M. Patch8Elliud M. Muli9Abdulaziz S. Alqarni10Michael H. Allsopp11Amro Zayed12Department of Biology York University Toronto Ontario CanadaDepartment of Biology York University Toronto Ontario CanadaDepartment of Biology York University Toronto Ontario CanadaDepartment of Biology York University Toronto Ontario CanadaDepartment of Biology York University Toronto Ontario CanadaDepartment of Biology York University Toronto Ontario CanadaBehaviour, Ecology and Evolution Laboratory, School of Life and Environmental Sciences University of Sydney Sydney AustraliaDepartment of Animal Production and Preventive Veterinary Medicine, School of Veterinary Medicine and Animal Science São Paulo State University (UNESP) Botucatu São Paulo BrazilDepartment of Entomology The Pennsylvania State University State College Pennsylvania USADepartment of Life Science South Eastern Kenya University (SEKU) Kitui KenyaDepartment of Plant Protection, College of Food and Agriculture Sciences King Saud University Riyadh Saudi ArabiaPlant Protection & Health Agricultural Research Council Stellenbosch South AfricaDepartment of Biology York University Toronto Ontario CanadaABSTRACT Hybrid populations of Africanized honey bees (scutellata‐hybrids), notable for their defensive behaviour, have spread rapidly throughout South and North America since their unintentional introduction. Although their migration has slowed, the large‐scale trade and movement of honey bee queens and colonies raise concern over the accidental importation of scutellata‐hybrids to previously unoccupied areas. Therefore, developing an accurate and robust assay to detect scutellata‐hybrids is an important first step toward mitigating risk. Here, we used an extensive population genomic dataset to assess the genomic composition of Apis mellifera native populations and patterns of genetic admixture in North and South American commercial honey bees. We used this dataset to develop a SNP assay, where 80 markers, combined with machine learning classification, can accurately differentiate between scutellata‐hybrids and non‐scutellata‐hybrid commercial colonies. The assay was validated on 1263 individuals from colonies located in Canada, the United States, Australia and Brazil. Notably, we demonstrate that using a reduced SNP set of as few as 10 loci can still provide accurate results.https://doi.org/10.1002/ece3.70554Africanized honey beeApis melliferabiomonitoringclassificationmachine learning
spellingShingle Kathleen A. Dogantzis
Harshilkumar Patel
Stephen Rose
Ida M. Conflitti
Alivia Dey
Tanushree Tiwari
Nadine C. Chapman
Samir M. Kadri
Harland M. Patch
Elliud M. Muli
Abdulaziz S. Alqarni
Michael H. Allsopp
Amro Zayed
Accurate Detection of scutellata‐Hybrids (Africanized Bees) Using a SNP‐Based Diagnostic Assay
Ecology and Evolution
Africanized honey bee
Apis mellifera
biomonitoring
classification
machine learning
title Accurate Detection of scutellata‐Hybrids (Africanized Bees) Using a SNP‐Based Diagnostic Assay
title_full Accurate Detection of scutellata‐Hybrids (Africanized Bees) Using a SNP‐Based Diagnostic Assay
title_fullStr Accurate Detection of scutellata‐Hybrids (Africanized Bees) Using a SNP‐Based Diagnostic Assay
title_full_unstemmed Accurate Detection of scutellata‐Hybrids (Africanized Bees) Using a SNP‐Based Diagnostic Assay
title_short Accurate Detection of scutellata‐Hybrids (Africanized Bees) Using a SNP‐Based Diagnostic Assay
title_sort accurate detection of scutellata hybrids africanized bees using a snp based diagnostic assay
topic Africanized honey bee
Apis mellifera
biomonitoring
classification
machine learning
url https://doi.org/10.1002/ece3.70554
work_keys_str_mv AT kathleenadogantzis accuratedetectionofscutellatahybridsafricanizedbeesusingasnpbaseddiagnosticassay
AT harshilkumarpatel accuratedetectionofscutellatahybridsafricanizedbeesusingasnpbaseddiagnosticassay
AT stephenrose accuratedetectionofscutellatahybridsafricanizedbeesusingasnpbaseddiagnosticassay
AT idamconflitti accuratedetectionofscutellatahybridsafricanizedbeesusingasnpbaseddiagnosticassay
AT aliviadey accuratedetectionofscutellatahybridsafricanizedbeesusingasnpbaseddiagnosticassay
AT tanushreetiwari accuratedetectionofscutellatahybridsafricanizedbeesusingasnpbaseddiagnosticassay
AT nadinecchapman accuratedetectionofscutellatahybridsafricanizedbeesusingasnpbaseddiagnosticassay
AT samirmkadri accuratedetectionofscutellatahybridsafricanizedbeesusingasnpbaseddiagnosticassay
AT harlandmpatch accuratedetectionofscutellatahybridsafricanizedbeesusingasnpbaseddiagnosticassay
AT elliudmmuli accuratedetectionofscutellatahybridsafricanizedbeesusingasnpbaseddiagnosticassay
AT abdulazizsalqarni accuratedetectionofscutellatahybridsafricanizedbeesusingasnpbaseddiagnosticassay
AT michaelhallsopp accuratedetectionofscutellatahybridsafricanizedbeesusingasnpbaseddiagnosticassay
AT amrozayed accuratedetectionofscutellatahybridsafricanizedbeesusingasnpbaseddiagnosticassay