Shaping current European mitochondrial haplogroup frequency in response to infection: the case of SARS-CoV-2 severity

Shaping current European mitochondrial haplogroup frequency in response to infection: the case of SARS-CoV-2 severity

Abstract The frequency of mitochondrial DNA haplogroups (mtDNA-HG) in humans is known to be shaped by migration and repopulation. Mounting evidence indicates that mtDNA-HG are not phenotypically neutral, and selection may contribute to its distribution. Haplogroup H, the most abundant in Europe, imp...

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Main Authors: José Luis Cabrera-Alarcon, Raquel Cruz, Marina Rosa-Moreno, Ana Latorre-Pellicer, Silvia Diz de Almeida, Scourge Cohort Group, José A. Riancho, Augusto Rojas-Martinez, Carlos Flores, Pablo Lapunzina, Fátima Sánchez-Cabo, Ángel Carracedo, José Antonio Enriquez
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-07314-y
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