Current state of prostate cancer treatment and future strategies
Prostate cancer (PCa) is the most common malignancy in men. It forms heterogeneous PCa masses with lining epithelial cells that require androgen signaling, and heterogeneous PCa masses can metastasize to lymph nodes and bone, making early diagnosis and treatment critical. PCa treatments include c...
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| Format: | Article |
| Language: | English |
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MRE Press
2024-11-01
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| Series: | Journal of Men's Health |
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| Online Access: | https://oss.jomh.org/files/article/20230928-100/pdf/JOMH2024041401.pdf |
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| _version_ | 1846126908573483008 |
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| author | Yeonhee Pyo Ki Han Kwon |
| author_facet | Yeonhee Pyo Ki Han Kwon |
| author_sort | Yeonhee Pyo |
| collection | DOAJ |
| description | Prostate cancer (PCa) is the most common malignancy in men. It forms
heterogeneous PCa masses with lining epithelial cells that require androgen
signaling, and heterogeneous PCa masses can metastasize to lymph nodes and bone,
making early diagnosis and treatment critical. PCa treatments include chemical
castration, surgical resection, chemotherapy, hormonal changes, and androgen
deprivation therapy. Diagnosis begins with a digital rectal exam (DRE) or
prostate-specific antigen, and is often associated with a negative prognosis and
pain. Furthermore, malignancy metastasizes or recurs to the bone. It is vital to
develop personalized treatment based on the understanding of cancer
pathophysiology. PCa is an aggressive multifactorial disease being focused in
men’s health research. PCa handling is crucial in men’s survival. It is
constantly studied for diagnosis, prevention and treatment. This article reviews
it from therapeutic perspective. It thus summarizes current and emerging
therapeutic strategies and biomarkers for PCa. |
| format | Article |
| id | doaj-art-f65642b7b5004e23b7838715db14e66e |
| institution | Kabale University |
| issn | 1875-6867 1875-6859 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | MRE Press |
| record_format | Article |
| series | Journal of Men's Health |
| spelling | doaj-art-f65642b7b5004e23b7838715db14e66e2024-12-12T08:20:00ZengMRE PressJournal of Men's Health1875-68671875-68592024-11-01201191810.22514/jomh.2024.181S1875-6867(24)00289-6Current state of prostate cancer treatment and future strategiesYeonhee Pyo0Ki Han Kwon1Department of Beauty Cosmetics, College of Biomedical and Health Science, Konkuk University, 27478 Chungju, Republic of KoreaCollege of General Education, Kookmin University, 02707 Seoul, Republic of KoreaProstate cancer (PCa) is the most common malignancy in men. It forms heterogeneous PCa masses with lining epithelial cells that require androgen signaling, and heterogeneous PCa masses can metastasize to lymph nodes and bone, making early diagnosis and treatment critical. PCa treatments include chemical castration, surgical resection, chemotherapy, hormonal changes, and androgen deprivation therapy. Diagnosis begins with a digital rectal exam (DRE) or prostate-specific antigen, and is often associated with a negative prognosis and pain. Furthermore, malignancy metastasizes or recurs to the bone. It is vital to develop personalized treatment based on the understanding of cancer pathophysiology. PCa is an aggressive multifactorial disease being focused in men’s health research. PCa handling is crucial in men’s survival. It is constantly studied for diagnosis, prevention and treatment. This article reviews it from therapeutic perspective. It thus summarizes current and emerging therapeutic strategies and biomarkers for PCa.https://oss.jomh.org/files/article/20230928-100/pdf/JOMH2024041401.pdfprostate cancertreatment strategiestarget agentbiomarkermen’s health |
| spellingShingle | Yeonhee Pyo Ki Han Kwon Current state of prostate cancer treatment and future strategies Journal of Men's Health prostate cancer treatment strategies target agent biomarker men’s health |
| title | Current state of prostate cancer treatment and future strategies |
| title_full | Current state of prostate cancer treatment and future strategies |
| title_fullStr | Current state of prostate cancer treatment and future strategies |
| title_full_unstemmed | Current state of prostate cancer treatment and future strategies |
| title_short | Current state of prostate cancer treatment and future strategies |
| title_sort | current state of prostate cancer treatment and future strategies |
| topic | prostate cancer treatment strategies target agent biomarker men’s health |
| url | https://oss.jomh.org/files/article/20230928-100/pdf/JOMH2024041401.pdf |
| work_keys_str_mv | AT yeonheepyo currentstateofprostatecancertreatmentandfuturestrategies AT kihankwon currentstateofprostatecancertreatmentandfuturestrategies |