Shengqiyichang decoction regulates antitumor immunity in colorectal cancer by downregulating lymphocyte antigen 6 family member G6D via the protein kinase B/p38 mitogen-activated protein kinase signaling pathway

Shengqiyichang decoction regulates antitumor immunity in colorectal cancer by downregulating lymphocyte antigen 6 family member G6D via the protein kinase B/p38 mitogen-activated protein kinase signaling pathway

The traditional Chinese medicine (TCM) formulation Shengqiyichang Decoction (SQYCD) has been reported to stimulate host immunity, and it has been administered for the treatment of colorectal cancer (CRC). Here, we applied network and bioinformatics analyses to elucidate the mechanisms by which SQYCD...

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Bibliographic Details
Main Authors: Run Xing Luo, Huai Liang Li, Yu Xiang Jia, Meng Gao, Zhao Yang Gao, Yi Ji, Shan Deng, Jie Ge Huo, Jian Zhang, Dong Jian Zhang
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Heliyon
Subjects:
Shengqiyichang decoction
Traditional Chinese medicine
Treg cells
Anti-tumor immunity
AKT/P38α signaling pathways
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402415102X
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