Age-Dependent DNA Methylation Variability on the X-Chromosome in Male and Female Twins

Age-Dependent DNA Methylation Variability on the X-Chromosome in Male and Female Twins

We aimed to explore the age-dependent epigenetic variability on the X-chromosome with consideration of X-chromosome inactivation by applying a sex-stratified regression analysis to DNA methylation array data on X-linked CpGs in aging identical twins. We found 13 X-linked CpGs showing age-related sig...

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Bibliographic Details
Main Authors:	Qihua Tan, Hikmat Alo, Marianne Nygaard, Mette Sørensen, Alisa Saleh, Jonas Mengel-From, Kaare Christensen
Format:	Article
Language:	English
Published:	MDPI AG 2024-11-01
Series:	Epigenomes
Subjects:	epigenetic instability X-linked DNA methylation aging twins mortality
Online Access:	https://www.mdpi.com/2075-4655/8/4/43
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