Inactivation of the conserved protease LonA increases production of xylanase and amylase in Bacillus subtilis

Inactivation of the conserved protease LonA increases production of xylanase and amylase in Bacillus subtilis

Abstract Background Bacillus subtilis is widely used for industrial enzyme production due to its capacity to efficiently secrete proteins. However, secretion efficiency of enzymes varies widely, and optimizing secretion is crucial to make production commercially viable. Previously, we have shown tha...

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Bibliographic Details
Main Authors: Biwen Wang, Mariah B. M. J. Kes, Anna C. H. van den Berg van Saparoea, Gaurav Dugar, Joen Luirink, Leendert W. Hamoen
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Microbial Cell Factories
Subjects:
Bacillus
Xylanase
Amylase
Secretion
Transcriptome profiling
Ribosome profiling
Online Access:https://doi.org/10.1186/s12934-024-02616-6
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