Mechanistic insights into 125I seed implantation therapy for Cholangiocarcinoma: focus on ROS-Mediated apoptosis and the role of GPX2
Abstract Objectives Cholangiocarcinoma (CCA) is a rare tumor with a poor prognosis and poses significant therapeutic challenges. Herein, we investigated the mechanism of efficacy of 125I seed implantation therapy in CCA, focusing on the induction of reactive oxygen species (ROS)-mediated apoptosis a...
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Main Authors: | Jun Luo, Zheng Yao, Weiren Liang, Danjun Song, Hui Zeng, Yi Jiang, Zhehan Bao, Jiaping Zheng, Yinan Ding |
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Format: | Article |
Language: | English |
Published: |
Springer
2024-06-01
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Series: | Journal of Cancer Research and Clinical Oncology |
Subjects: | |
Online Access: | https://doi.org/10.1007/s00432-024-05840-0 |
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