Crisdesalazine alleviates inflammation in an experimental autoimmune encephalomyelitis multiple sclerosis mouse model by regulating the immune system

Crisdesalazine alleviates inflammation in an experimental autoimmune encephalomyelitis multiple sclerosis mouse model by regulating the immune system

Abstract Microglia/macrophages participate in the development of and recovery from experimental autoimmune encephalomyelitis (EAE), and the macrophage M1 (pro-inflammatory)/M2 (anti-inflammatory) phase transition is involved in EAE disease progression. We evaluated the efficacy of crisdesalazine (a...

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Main Authors:	Su-Min Park, Yong-Hun Oh, Ga-Hyun Lim, Ju-Hyun An, Jin-Hwan Lee, Byoung-Joo Gwag, So-Jung Won, Kyoung-Won Seo, Hwa-Young Youn
Format:	Article
Language:	English
Published:	BMC 2025-01-01
Series:	BMC Neuroscience
Subjects:	Anti-inflammation Crisdesalazine Experimental autoimmune encephalomyelitis Microsomal prostaglandin E2 synthase-1 Macrophage
Online Access:	https://doi.org/10.1186/s12868-024-00920-w
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