Genetic Incorporation of a Herpes Simplex Virus Type 1 Thymidine Kinase and Firefly Luciferase Fusion into the Adenovirus Protein IX for Functional Display on the Virion

Genetic Incorporation of a Herpes Simplex Virus Type 1 Thymidine Kinase and Firefly Luciferase Fusion into the Adenovirus Protein IX for Functional Display on the Virion

An advantage of the adenoviral vector is its molecular flexibility, which allows for vector tropism modifications for the purpose of cell targeting. In addition to targeting ligands, the capacity to incorporate heterologous peptides has allowed capsid incorporation of other functionalities. We have...

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Bibliographic Details
Main Authors: Qiana L. Matthews, Don A. Sibley, Hongju Wu, Jing Li, Mariam A. Stoff-Khalili, Reinhard Waehler, J. Michael Mathis, David T. Curiel
Format: Article
Language:English
Published: SAGE Publishing 2006-10-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2006.00029
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