Efficacy and safety of combined Kahook Dual Blade goniotomy with phacoemulsification in Chinese patients with primary open angle glaucoma
AIM: To report the one-year surgical outcome Kahook Dual Blade goniotomy combined with phacoemulsification (KDB-Phaco) in Chinese patients with primary open angle glaucoma (POAG). METHODS: This is a retrospective study included 43 eyes of 28 Chinese POAG patients with cataract who accepted KDB-Phaco...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Press of International Journal of Ophthalmology (IJO PRESS)
2025-02-01
|
| Series: | International Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/en_publish/2025/2/20250210.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1841526994427183104 |
|---|---|
| author | Lin Fu Jiang-Tao Lou Yue Guo Pei-Juan Wang Rong-Rong Le Shu-Xia Xu Guo-Xing Li Yuan-Bo Liang |
| author_facet | Lin Fu Jiang-Tao Lou Yue Guo Pei-Juan Wang Rong-Rong Le Shu-Xia Xu Guo-Xing Li Yuan-Bo Liang |
| author_sort | Lin Fu |
| collection | DOAJ |
| description | AIM: To report the one-year surgical outcome Kahook Dual Blade goniotomy combined with phacoemulsification (KDB-Phaco) in Chinese patients with primary open angle glaucoma (POAG). METHODS: This is a retrospective study included 43 eyes of 28 Chinese POAG patients with cataract who accepted KDB-Phaco and followed-up for 12mo. Intraocular pressure (IOP), glaucoma medications and surgical complications were recorded. Success 1 and success 2 was defined as 5-21 mm Hg and 5-18 mm Hg, and success plus was determined if additional criteria of IOP reduction ≥20% from baseline was reached. A corrected IOP by adding 3 mm Hg for each medication was used to do correlation test. Cox's proportional hazards regression model was used to test the hazard ratio for factors associated with surgical success. RESULTS: After a 12-month follow up, the IOP decreased from 28.1±6.3 to 13.8±3.0 mm Hg (47.92% reduction, P<0.001), and the medications used decreased from 2.0 (1.0) to 0.0 (0.0) (95% reduction, P<0.001). The mean IOP of all postoperative visits were lower than preoperative IOP (all P<0.001), so as the number of glaucoma medications (all P<0.001). Complete success 1 and qualified success 1 were 87.80% and 100.00% respectively. The complete success 1 plus and qualified success 1 plus were 85.37% and 97.56%, respectively. Totally 82.93% and 90.24% of patients got complete success 2 and qualified success 2 while 80.49% and 87.80% of patients satisfied complete success 2 plus and qualified success 2 plus. Age (r=-0.511, P=0.001) and visual acuity (VA; r=-0.321, P=0.041) were negatively correlated with postoperative corrected IOP at 12mo, while anterior chamber depth (r=0.432, P=0.005), mean deviation (r=0.617, P<0.001) and visual field index (r=0.524, P<0.001) were positively correlated with it. Preoperative VA (OR=33.092, P=0.004) and MD (OR=1.481, P=0.018) were hazard factors associated with failure based on qualified success as 18 mm Hg. The main complications of KDB were hyphema (9.30%), IOP spike (11.63%) and peripheral anterior synechia (6.98%). CONCLUSION: KDB goniotomy is a safe and effective in the treatment for Chinese POAG patients. Preoperative VA and mean deviation may predict the surgical success. |
| format | Article |
| id | doaj-art-f5c6eff2283a4f72b41f361fab5e7a1f |
| institution | Kabale University |
| issn | 2222-3959 2227-4898 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | International Journal of Ophthalmology |
| spelling | doaj-art-f5c6eff2283a4f72b41f361fab5e7a1f2025-01-16T07:54:35ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982025-02-0118226827410.18240/ijo.2025.02.1020250210Efficacy and safety of combined Kahook Dual Blade goniotomy with phacoemulsification in Chinese patients with primary open angle glaucomaLin Fu0Jiang-Tao Lou1Yue Guo2Pei-Juan Wang3Rong-Rong Le4Shu-Xia Xu5Guo-Xing Li6Yuan-Bo Liang7Guo-Xing Li. National Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325003, Zhejiang Province, China. lgx9872@eye.ac.cnNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325003, Zhejiang Province, ChinaNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325003, Zhejiang Province, ChinaNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325003, Zhejiang Province, ChinaNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325003, Zhejiang Province, ChinaNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325003, Zhejiang Province, ChinaNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325003, Zhejiang Province, ChinaNational Clinical Research Center for Ocular Diseases, Eye Hospital, Wenzhou Medical University, Wenzhou 325003, Zhejiang Province, ChinaAIM: To report the one-year surgical outcome Kahook Dual Blade goniotomy combined with phacoemulsification (KDB-Phaco) in Chinese patients with primary open angle glaucoma (POAG). METHODS: This is a retrospective study included 43 eyes of 28 Chinese POAG patients with cataract who accepted KDB-Phaco and followed-up for 12mo. Intraocular pressure (IOP), glaucoma medications and surgical complications were recorded. Success 1 and success 2 was defined as 5-21 mm Hg and 5-18 mm Hg, and success plus was determined if additional criteria of IOP reduction ≥20% from baseline was reached. A corrected IOP by adding 3 mm Hg for each medication was used to do correlation test. Cox's proportional hazards regression model was used to test the hazard ratio for factors associated with surgical success. RESULTS: After a 12-month follow up, the IOP decreased from 28.1±6.3 to 13.8±3.0 mm Hg (47.92% reduction, P<0.001), and the medications used decreased from 2.0 (1.0) to 0.0 (0.0) (95% reduction, P<0.001). The mean IOP of all postoperative visits were lower than preoperative IOP (all P<0.001), so as the number of glaucoma medications (all P<0.001). Complete success 1 and qualified success 1 were 87.80% and 100.00% respectively. The complete success 1 plus and qualified success 1 plus were 85.37% and 97.56%, respectively. Totally 82.93% and 90.24% of patients got complete success 2 and qualified success 2 while 80.49% and 87.80% of patients satisfied complete success 2 plus and qualified success 2 plus. Age (r=-0.511, P=0.001) and visual acuity (VA; r=-0.321, P=0.041) were negatively correlated with postoperative corrected IOP at 12mo, while anterior chamber depth (r=0.432, P=0.005), mean deviation (r=0.617, P<0.001) and visual field index (r=0.524, P<0.001) were positively correlated with it. Preoperative VA (OR=33.092, P=0.004) and MD (OR=1.481, P=0.018) were hazard factors associated with failure based on qualified success as 18 mm Hg. The main complications of KDB were hyphema (9.30%), IOP spike (11.63%) and peripheral anterior synechia (6.98%). CONCLUSION: KDB goniotomy is a safe and effective in the treatment for Chinese POAG patients. Preoperative VA and mean deviation may predict the surgical success.http://ies.ijo.cn/en_publish/2025/2/20250210.pdfkahook dual blade goniotomyprimary open angle glaucomasuccess raterisk factors |
| spellingShingle | Lin Fu Jiang-Tao Lou Yue Guo Pei-Juan Wang Rong-Rong Le Shu-Xia Xu Guo-Xing Li Yuan-Bo Liang Efficacy and safety of combined Kahook Dual Blade goniotomy with phacoemulsification in Chinese patients with primary open angle glaucoma International Journal of Ophthalmology kahook dual blade goniotomy primary open angle glaucoma success rate risk factors |
| title | Efficacy and safety of combined Kahook Dual Blade goniotomy with phacoemulsification in Chinese patients with primary open angle glaucoma |
| title_full | Efficacy and safety of combined Kahook Dual Blade goniotomy with phacoemulsification in Chinese patients with primary open angle glaucoma |
| title_fullStr | Efficacy and safety of combined Kahook Dual Blade goniotomy with phacoemulsification in Chinese patients with primary open angle glaucoma |
| title_full_unstemmed | Efficacy and safety of combined Kahook Dual Blade goniotomy with phacoemulsification in Chinese patients with primary open angle glaucoma |
| title_short | Efficacy and safety of combined Kahook Dual Blade goniotomy with phacoemulsification in Chinese patients with primary open angle glaucoma |
| title_sort | efficacy and safety of combined kahook dual blade goniotomy with phacoemulsification in chinese patients with primary open angle glaucoma |
| topic | kahook dual blade goniotomy primary open angle glaucoma success rate risk factors |
| url | http://ies.ijo.cn/en_publish/2025/2/20250210.pdf |
| work_keys_str_mv | AT linfu efficacyandsafetyofcombinedkahookdualbladegoniotomywithphacoemulsificationinchinesepatientswithprimaryopenangleglaucoma AT jiangtaolou efficacyandsafetyofcombinedkahookdualbladegoniotomywithphacoemulsificationinchinesepatientswithprimaryopenangleglaucoma AT yueguo efficacyandsafetyofcombinedkahookdualbladegoniotomywithphacoemulsificationinchinesepatientswithprimaryopenangleglaucoma AT peijuanwang efficacyandsafetyofcombinedkahookdualbladegoniotomywithphacoemulsificationinchinesepatientswithprimaryopenangleglaucoma AT rongrongle efficacyandsafetyofcombinedkahookdualbladegoniotomywithphacoemulsificationinchinesepatientswithprimaryopenangleglaucoma AT shuxiaxu efficacyandsafetyofcombinedkahookdualbladegoniotomywithphacoemulsificationinchinesepatientswithprimaryopenangleglaucoma AT guoxingli efficacyandsafetyofcombinedkahookdualbladegoniotomywithphacoemulsificationinchinesepatientswithprimaryopenangleglaucoma AT yuanboliang efficacyandsafetyofcombinedkahookdualbladegoniotomywithphacoemulsificationinchinesepatientswithprimaryopenangleglaucoma |