Influence of sodium Bituminosulfonate and Doxycycline on signal molecules relevant for rosacea symptoms

Influence of sodium Bituminosulfonate and Doxycycline on signal molecules relevant for rosacea symptoms

Abstract Rosacea is treated among others by doxycycline and sodium bituminosulfonate dry substance (SBDS). We addressed the molecular mechanism(s) underlying the therapeutic benefit of SBDS and doxycycline. Therefore, we investigated whether SBDS or doxycycline regulates the expression of signal mol...

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Bibliographic Details
Main Authors: Ann Sophie Rein, Marina Henke, Sophie Brünner, Sonja Luckhardt, Anna-Lena Zodel, Annette Sethmann, Susanne Schiffmann
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Sodium Bituminosulfonate
Doxycycline
Rosacea
INOS
VEGF
LL37
Online Access:https://doi.org/10.1038/s41598-025-02796-0
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