The Effect of Thyroid Nodule Size and Characteristics on the Accuracy of Fine-Needle Aspiration Biopsy and the Risk of Malignancy

Objective: Ultrasound evaluation of nodule characteristics and FNAB is a simple, cost-effective method. However, its reliability in large nodules is controversial. This study aims to examine the impact of thyroid nodule size and characteristics on malignancy risk and FNAB ac...

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Main Authors: Mehmet Alperen Avcı, Can Akgün, Mustafa Gün, Selim Tamam, Meltem Türk
Format: Article
Language:English
Published: Hitit University 2024-10-01
Series:Hitit Medical Journal
Online Access:https://dergipark.org.tr/tr/doi/10.52827/hititmedj.1501055
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author Mehmet Alperen Avcı
Can Akgün
Mustafa Gün
Selim Tamam
Meltem Türk
author_facet Mehmet Alperen Avcı
Can Akgün
Mustafa Gün
Selim Tamam
Meltem Türk
author_sort Mehmet Alperen Avcı
collection DOAJ
description Objective: Ultrasound evaluation of nodule characteristics and FNAB is a simple, cost-effective method. However, its reliability in large nodules is controversial. This study aims to examine the impact of thyroid nodule size and characteristics on malignancy risk and FNAB accuracy as evaluated by ultrasound. Material and Method: This retrospective study included 522 patients who underwent thyroidectomy between January 1, 2020, and January 1, 2024. The data included the patients’ age, gender, preoperative thyroid ultrasound findings, preoperative FNAB pathology findings, operation notes, and postoperative pathology results colleected from hospital archives. Kruskal-Wallis Variance Analysis, ROC (Receiver Operating Characteristics) curve analysis, Bonferroni Corrected Mann-Whitney U Test, Chi-Square Tests, were used at statistical analysis. Results: The median age was 49.45 years. The threshold value for nodule size in the X plane was 27 mm (p27 mm.
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institution Kabale University
issn 2687-4717
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publishDate 2024-10-01
publisher Hitit University
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series Hitit Medical Journal
spelling doaj-art-f55e4863b2024d6f910a11234b0e19ed2025-01-12T07:11:01ZengHitit UniversityHitit Medical Journal2687-47172024-10-016332133010.52827/hititmedj.1501055 The Effect of Thyroid Nodule Size and Characteristics on the Accuracy of Fine-Needle Aspiration Biopsy and the Risk of Malignancy Mehmet Alperen Avcı0https://orcid.org/0000-0003-3911-2686Can Akgün1https://orcid.org/0000-0002-8367-0768Mustafa Gün2https://orcid.org/0000-0002-2343-0316Selim Tamam3https://orcid.org/0000-0002-2924-1874Meltem Türk4https://orcid.org/0000-0003-3975-331XSAMSUN ÜNİVERSİTESİ, TIP FAKÜLTESİSAMSUN UNIVERSITYSAMSUN UNIVERSITYANKARA ÜNİVERSİTESİ, TIP FAKÜLTESİ, TIP PR.Ordu Üniversitesi Eğitim Araştırma Hastanesi Objective: Ultrasound evaluation of nodule characteristics and FNAB is a simple, cost-effective method. However, its reliability in large nodules is controversial. This study aims to examine the impact of thyroid nodule size and characteristics on malignancy risk and FNAB accuracy as evaluated by ultrasound. Material and Method: This retrospective study included 522 patients who underwent thyroidectomy between January 1, 2020, and January 1, 2024. The data included the patients’ age, gender, preoperative thyroid ultrasound findings, preoperative FNAB pathology findings, operation notes, and postoperative pathology results colleected from hospital archives. Kruskal-Wallis Variance Analysis, ROC (Receiver Operating Characteristics) curve analysis, Bonferroni Corrected Mann-Whitney U Test, Chi-Square Tests, were used at statistical analysis. Results: The median age was 49.45 years. The threshold value for nodule size in the X plane was 27 mm (p27 mm.https://dergipark.org.tr/tr/doi/10.52827/hititmedj.1501055
spellingShingle Mehmet Alperen Avcı
Can Akgün
Mustafa Gün
Selim Tamam
Meltem Türk
The Effect of Thyroid Nodule Size and Characteristics on the Accuracy of Fine-Needle Aspiration Biopsy and the Risk of Malignancy
Hitit Medical Journal
title The Effect of Thyroid Nodule Size and Characteristics on the Accuracy of Fine-Needle Aspiration Biopsy and the Risk of Malignancy
title_full The Effect of Thyroid Nodule Size and Characteristics on the Accuracy of Fine-Needle Aspiration Biopsy and the Risk of Malignancy
title_fullStr The Effect of Thyroid Nodule Size and Characteristics on the Accuracy of Fine-Needle Aspiration Biopsy and the Risk of Malignancy
title_full_unstemmed The Effect of Thyroid Nodule Size and Characteristics on the Accuracy of Fine-Needle Aspiration Biopsy and the Risk of Malignancy
title_short The Effect of Thyroid Nodule Size and Characteristics on the Accuracy of Fine-Needle Aspiration Biopsy and the Risk of Malignancy
title_sort effect of thyroid nodule size and characteristics on the accuracy of fine needle aspiration biopsy and the risk of malignancy
url https://dergipark.org.tr/tr/doi/10.52827/hititmedj.1501055
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