Longitudinal evaluation of common and unique brain-networks in variants of primary progressive aphasia

Abstract Background and objectives The two variants of primary progressive aphasia (PPA) with Frontotemporal dementia pathology- semantic (svPPA) and non-fluent (nfvPPA) exhibit both shared and distinct features. The phenotypic heterogeneity stems from alterations in underlying brain networks. Inves...

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Main Authors: Rajan Kashyap, Rose Dawn Bharath, Changsong Zhou, Kyrana Tsapkini, John E. Desmond, SH Annabel Chen, Kaviraja Udupa, PT Sivakumar, Sagarika Bhattacharjee
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Alzheimer’s Research & Therapy
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Online Access:https://doi.org/10.1186/s13195-025-01800-z
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