G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo

G. vaginalis increases HSV-2 infection by decreasing vaginal barrier integrity and increasing inflammation in vivo

IntroductionClinically, a dysbiotic vaginal microbiota (VMB) colonized with anaerobic species such as Gardnerella vaginalis has been linked to increased susceptibility to viral sexually transmitted infections (STIs) such as Herpes Simplex Virus Type 2 (HSV-2). The mechanism is poorly understood due...

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Bibliographic Details
Main Authors:	Nuzhat Rahman, M. Firoz Mian, Christina L. Hayes, Aisha Nazli, Charu Kaushic
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-11-01
Series:	Frontiers in Immunology
Subjects:	vaginal microbiota (VMB) Lactobacillus bacterial vaginosis herpes simplex virus inflammation barrier integrity
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1487726/full
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