Microbiome and Prostate Cancer

According to scientific research, the microbiome and the likelihood of developing cancer are causally related. Current evidence indicates the probable absence of bacteria in a disease-free prostate. There is still a lack of conclusive evidence linking the diversity of gut microbiota and prostate...

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Bibliographic Details
Main Author: Ivana Mareković
Format: Article
Language:English
Published: Sestre Milosrdnice University hospital, Institute of Clinical Medical Research 2024-01-01
Series:Acta Clinica Croatica
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Online Access:https://hrcak.srce.hr/file/467265
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Summary:According to scientific research, the microbiome and the likelihood of developing cancer are causally related. Current evidence indicates the probable absence of bacteria in a disease-free prostate. There is still a lack of conclusive evidence linking the diversity of gut microbiota and prostate cancer. The development and spread of prostate cancer seem to be significantly influenced by inflammation. With next generation sequencing methods, different bacterial species were found in the gut microbiome of patients with prostate cancer. The microbiome can affect the effectiveness of various chemotherapeutic drugs by altering the immune system and metabolic processes. Patients with and without radiation enteropathy have different microbiomes. The possibility of risk assessment, prevention, or treatment of radiation-induced enteropathy can be revealed by microbiome testing before and during pelvic radiation. It is essential to understand the complex relationship between the microbiome and prostate cancer. The manipulation of gut microbiome may enhance the effectiveness of cancer treatments. The opportunity to use the microbiome as a target for the prevention of this cancerous condition as well as an additional intriguing option in the management of prostate cancer and a more comprehensive therapeutic approach should not be missed.
ISSN:0353-9466
1333-9451