In vitro vascular differentiation system efficiently produces natural killer cells for cancer immunotherapies

In vitro vascular differentiation system efficiently produces natural killer cells for cancer immunotherapies

Background Immunotherapeutic innovation is crucial for limited operability tumors. CAR T-cell therapy displayed reduced efficiency against glioblastoma (GBM), likely due to mutations underlying disease progression. Natural Killer cells (NKs) detect cancer cells despite said mutations – demonstrating...

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Bibliographic Details
Main Authors: Yekaterina Galat, Yuchen Du, Mariana Perepitchka, Xiao-Nan Li, Irina V Balyasnikova, William T Tse, Svetlana Dambaeva, Sylvia Schneiderman, Philip M Iannaccone, Oren Becher, Douglas K Graham, Vasiliy Galat
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:OncoImmunology
Subjects:
hPSCs
iPSCs
Hematopoietic Differentiation
Organoid
hPSC-Natural Killer Cells
Engraftment
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2023.2240670
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https://www.tandfonline.com/doi/10.1080/2162402X.2023.2240670

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