Metabolic syndrome extenuation in rat model by feeding Stevia rebaudiana Bertoni cookies

Stevia rebaudiana is zero-calorie bio-sweetener and furnishes the best nutrition out of it. The study was conducted to characterize the extracts from water, ethanol, methanol, and supercritical fluid for Steviosides/SGs. The compounds found in appreciable quantities were Stevioside (665.34 ± 27.27 t...

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Main Authors: Muhammad Farhan Jahangeer Chughtai, Imran Pasha, Samreen Ahsan, Tariq Mehmood, Muhammad Zubair Khalid, Muhammad Adil Farooq, Atif Liaqat, Adnan Khaliq, Saira Tanweer, Mădălina Ungureanu-Iuga, Ionica Cotovanu, Abdullah Ali Alkahtane, Saleh Alfarraj, Felix Kwashie Madilo
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Cogent Food & Agriculture
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Online Access:https://www.tandfonline.com/doi/10.1080/23311932.2024.2305513
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author Muhammad Farhan Jahangeer Chughtai
Imran Pasha
Samreen Ahsan
Tariq Mehmood
Muhammad Zubair Khalid
Muhammad Adil Farooq
Atif Liaqat
Adnan Khaliq
Saira Tanweer
Mădălina Ungureanu-Iuga
Ionica Cotovanu
Abdullah Ali Alkahtane
Saleh Alfarraj
Felix Kwashie Madilo
author_facet Muhammad Farhan Jahangeer Chughtai
Imran Pasha
Samreen Ahsan
Tariq Mehmood
Muhammad Zubair Khalid
Muhammad Adil Farooq
Atif Liaqat
Adnan Khaliq
Saira Tanweer
Mădălina Ungureanu-Iuga
Ionica Cotovanu
Abdullah Ali Alkahtane
Saleh Alfarraj
Felix Kwashie Madilo
author_sort Muhammad Farhan Jahangeer Chughtai
collection DOAJ
description Stevia rebaudiana is zero-calorie bio-sweetener and furnishes the best nutrition out of it. The study was conducted to characterize the extracts from water, ethanol, methanol, and supercritical fluid for Steviosides/SGs. The compounds found in appreciable quantities were Stevioside (665.34 ± 27.27 to 1107.95 ± 50.96 mg/kg), Rebaudioside A (383.38 ± 17.25 to 792.15 ± 38.02 mg/kg) and Steviol (357.26 ± 14.64 to 485.25 ± 22.32 mg/kg). Stevia cookies were prepared by replacing sucrose with Stevia powder (10%), water extract (1%), and supercritical extract (3%). Bio-efficacy rats modeling trials were done to check their impact against hyperglycemia and hypercholesterolemia. Blood glucose level was reduced from 4.54 to 7.00%, insulin level was increased by 4.27 to 6.13% due to diets enriched with stevia powder and extracts as compared to the control. In hypercholesterolemic rats, up surged cholesterol level was reported to reduce as a function of Stevia powder and extracts from 1.28 to 5.47%. Substantial increment in HDL, and reduction in LDL and triglycerides was recorded in Stevia leaves powder and extracts treatments by 2.79–6.66%, 2.68–4.16%, and 3.12–5.36, respectively. Stevia cookies administration in rats showed non-significant impact on the liver, renal, and hepatological parameters, while the safety of cookies was improved. Therefore, it can be concluded from the outcomes that in addition to sweetness, Stevia health health-beneficial effects make it suitable to be included in cookies.
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spelling doaj-art-f4ffe6f6ea1844d4bfb8ef02e58d0de52024-12-13T09:52:51ZengTaylor & Francis GroupCogent Food & Agriculture2331-19322024-12-0110110.1080/23311932.2024.2305513Metabolic syndrome extenuation in rat model by feeding Stevia rebaudiana Bertoni cookiesMuhammad Farhan Jahangeer Chughtai0Imran Pasha1Samreen Ahsan2Tariq Mehmood3Muhammad Zubair Khalid4Muhammad Adil Farooq5Atif Liaqat6Adnan Khaliq7Saira Tanweer8Mădălina Ungureanu-Iuga9Ionica Cotovanu10Abdullah Ali Alkahtane11Saleh Alfarraj12Felix Kwashie Madilo13Institute of Food Science and Technology, Faculty of Food, Health Science and Technology, Khwaja Fareed University Engineering and Information Technology, PakistanNational Institute of Food Science and Technology, Faculty of Food, Nutrition and Home Sciences, University of Agriculture, Faisalabad, PakistanInstitute of Food Science and Technology, Faculty of Food, Health Science and Technology, Khwaja Fareed University Engineering and Information Technology, PakistanInstitute of Food Science and Technology, Faculty of Food, Health Science and Technology, Khwaja Fareed University Engineering and Information Technology, PakistanDepartment of Food Science, Government College University Faisalabad, Faisalabad, PakistanInstitute of Food Science and Technology, Faculty of Food, Health Science and Technology, Khwaja Fareed University Engineering and Information Technology, PakistanInstitute of Food Science and Technology, Faculty of Food, Health Science and Technology, Khwaja Fareed University Engineering and Information Technology, PakistanInstitute of Food Science and Technology, Faculty of Food, Health Science and Technology, Khwaja Fareed University Engineering and Information Technology, PakistanDepartment of Food Science and Technology, Faculty of Agriculture and Environment, Baghdad ul Jadeed Campus, The Islamia University of Bahawalpur, PakistanIntegrated Center for Research, Development and Innovation in Advanced Materials, Nanotechnologies, and Distributed Systems for Fabrication and Control (MANSiD), “Ştefan cel Mare”, University of Suceava, Suceava, RomaniaFaculty of Food Engineering, “Ştefan cel Mare”, University of Suceava, Suceava, RomaniaDepartment of Zoology, College of Science, King Saud University, Riyadh, Saudi ArabiaDepartment of Zoology, College of Science, King Saud University, Riyadh, Saudi ArabiaDepartment of Food Science and Technology, Ho Technical University, Ho, GhanaStevia rebaudiana is zero-calorie bio-sweetener and furnishes the best nutrition out of it. The study was conducted to characterize the extracts from water, ethanol, methanol, and supercritical fluid for Steviosides/SGs. The compounds found in appreciable quantities were Stevioside (665.34 ± 27.27 to 1107.95 ± 50.96 mg/kg), Rebaudioside A (383.38 ± 17.25 to 792.15 ± 38.02 mg/kg) and Steviol (357.26 ± 14.64 to 485.25 ± 22.32 mg/kg). Stevia cookies were prepared by replacing sucrose with Stevia powder (10%), water extract (1%), and supercritical extract (3%). Bio-efficacy rats modeling trials were done to check their impact against hyperglycemia and hypercholesterolemia. Blood glucose level was reduced from 4.54 to 7.00%, insulin level was increased by 4.27 to 6.13% due to diets enriched with stevia powder and extracts as compared to the control. In hypercholesterolemic rats, up surged cholesterol level was reported to reduce as a function of Stevia powder and extracts from 1.28 to 5.47%. Substantial increment in HDL, and reduction in LDL and triglycerides was recorded in Stevia leaves powder and extracts treatments by 2.79–6.66%, 2.68–4.16%, and 3.12–5.36, respectively. Stevia cookies administration in rats showed non-significant impact on the liver, renal, and hepatological parameters, while the safety of cookies was improved. Therefore, it can be concluded from the outcomes that in addition to sweetness, Stevia health health-beneficial effects make it suitable to be included in cookies.https://www.tandfonline.com/doi/10.1080/23311932.2024.2305513Stevia rebaudianaSteviosideSteviolcookiesstevia leaves powderfood chemistry
spellingShingle Muhammad Farhan Jahangeer Chughtai
Imran Pasha
Samreen Ahsan
Tariq Mehmood
Muhammad Zubair Khalid
Muhammad Adil Farooq
Atif Liaqat
Adnan Khaliq
Saira Tanweer
Mădălina Ungureanu-Iuga
Ionica Cotovanu
Abdullah Ali Alkahtane
Saleh Alfarraj
Felix Kwashie Madilo
Metabolic syndrome extenuation in rat model by feeding Stevia rebaudiana Bertoni cookies
Cogent Food & Agriculture
Stevia rebaudiana
Stevioside
Steviol
cookies
stevia leaves powder
food chemistry
title Metabolic syndrome extenuation in rat model by feeding Stevia rebaudiana Bertoni cookies
title_full Metabolic syndrome extenuation in rat model by feeding Stevia rebaudiana Bertoni cookies
title_fullStr Metabolic syndrome extenuation in rat model by feeding Stevia rebaudiana Bertoni cookies
title_full_unstemmed Metabolic syndrome extenuation in rat model by feeding Stevia rebaudiana Bertoni cookies
title_short Metabolic syndrome extenuation in rat model by feeding Stevia rebaudiana Bertoni cookies
title_sort metabolic syndrome extenuation in rat model by feeding stevia rebaudiana bertoni cookies
topic Stevia rebaudiana
Stevioside
Steviol
cookies
stevia leaves powder
food chemistry
url https://www.tandfonline.com/doi/10.1080/23311932.2024.2305513
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