IL-6-induced long noncoding RNA MIR3142HG promotes tumorigenesis by interacting with thioredoxin-1 and STAT3 in human colorectal cancer

IL-6-induced long noncoding RNA MIR3142HG promotes tumorigenesis by interacting with thioredoxin-1 and STAT3 in human colorectal cancer

Abstract Background Colorectal cancer (CRC) is a prevalent and highly malignant neoplasm on a global scale, ranking as the second most widespread cause of cancer-associated death. Long noncoding RNAs (lncRNAs) control tumorigenic processes in CRC by modulating inflammatory signals. However, the prec...

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Bibliographic Details
Main Authors: Daoquan Fang, Qian Feng, Baojian Zhou, Yangyang Liu, Yichu Lian, Yihui Zhang, Dichen Yang, Xintong Liu, Xiaomeng Shi, Wuhua Ni, Lei Jiang
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cellular & Molecular Biology Letters
Subjects:
MIR3142HG
IL-6
STAT3
Trx-1
CRC
Online Access:https://doi.org/10.1186/s11658-025-00742-6
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