Microenvironment-confined kinetic elucidation and implementation of a DNA nano-phage with a shielded internal computing layer

Microenvironment-confined kinetic elucidation and implementation of a DNA nano-phage with a shielded internal computing layer

Abstract Multiple receptor analysis-based DNA molecular computation has been developed to mitigate the off-target effect caused by nonspecific expression of cell membrane receptors. However, it is quite difficult to involve nanobodies into molecular computation with programmed recognition order beca...

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Bibliographic Details
Main Authors: Decui Tang, Shuoyao He, Yani Yang, Yuqi Zeng, Mengyi Xiong, Ding Ding, Weijun Wei, Yifan Lyu, Xiao-Bing Zhang, Weihong Tan
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56219-9
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