α-Synuclein aggregation decreases cortico-amygdala connectivity and impairs social behavior in mice

α-Synuclein aggregation decreases cortico-amygdala connectivity and impairs social behavior in mice

Abnormal accumulation of insoluble α-synuclein (α-Syn) inclusions in neurons, neurites, and glial cells is the defining neuropathology of synucleinopathies, including Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy. Accumulation of α-Syn inclusions in the...

Full description

Saved in:
Bibliographic Details
Main Authors: Wei Zhou, Samuel Daniels, Vijay Singh, Marissa Menard, Martha L. Escobar Galvis, Hong-Yuan Chu
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Neurobiology of Disease
Subjects:
α-Synuclein
Synucleinopathies
Parkinson's disease
Medial prefrontal cortex
Amygdala
Electrophysiology
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996124003024
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items